Results 101 to 110 of about 20,796,690 (304)

Valosin‐containing protein counteracts ATP‐driven dissolution of FUS condensates through its ATPase activity in vitro

open access: yesFEBS Letters, EarlyView.
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura   +2 more
wiley   +1 more source

Part-time Employees Were Not Created Equal: Exploring How Part-time Groups Differ on Measures That Can Predict Employee Turnover Intention

open access: yes, 2009
This study built upon research by Martin and Sinclair (2007) who found the part-time employee group is made up of distinct groups that differ in their responses across a range of attitudinal variables (e.g.
Whistler, Hamish Tomas
core  

Diversity and complexity in neural organoids

open access: yesFEBS Letters, EarlyView.
Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley   +1 more source

Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation

open access: yesFEBS Letters, EarlyView.
Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz   +11 more
wiley   +1 more source

女性軍訓教官的職場困境:以已婚育有子女者為例的性別分析 A Gender Study of Married Female Military Instructors’ Work Experiences [PDF]

open access: yes臺灣教育社會學研究, 2006
本研究以「女性軍訓教官」的工作經驗為主,透過訪談八位女性軍訓教官,探討其在職場上因「性別」因素所造成之困境。綜合分析結果發現,女教官進入校園服務必須面臨的職場困境有下列三項:傳統性別角色的侷限、就業歧視、升遷的限制等。其中升遷限制除了性別歧視及制度設計因素外,父權社會結構因素亦造成女教官自我設限,降低追求成就之動機。 This qualitative research focuses on female military instructors’ work experiences.
楊櫻華 Ying-Hua Yang   +1 more
doaj  

An isoform of 14‐3‐3 protein regulates transbilayer lipid movement at the plasma membrane

open access: yesFEBS Letters, EarlyView.
Loss of 14‐3‐3ζ in CHO cells confers resistance to exogenous phosphatidylserine (PS) and impairs endocytosis‐independent inward flip‐flop of fluorescent PS at the plasma membrane. RNAi‐mediated knockdown reproduces this defect, while no additive effect is seen in ATP11C‐deficient cells.
Akiko Yamaji‐Hasegawa   +3 more
wiley   +1 more source

The ubiquitin ligase RNF115 is required for the clearance of damaged lysosomes

open access: yesFEBS Letters, EarlyView.
Upon lysosomal rupture, an E3 ubiquitin ligase RNF115 translocates from the cytosol to the damaged lysosomal membrane. Moreover, RNF115 depletion impairs the clearance of damaged lysosomes, identifying it as a key regulator of lysosomal quality control.
Sae Nakanaga   +3 more
wiley   +1 more source

Imam Javad’s Interaction with the Shiites Resident in Jebal Area of Iran [PDF]

open access: yesتاریخ اسلام, 2016
The process and quiddity of relationship of Iranians with the prophet’s family is one of the significant issues of Iran’s history in the Islamic era.  Is spite of great limitation, Imam Javad differently had relationship with Shiites resident in Iran ...
Seyed Mahmood Samani
doaj  

Part-time work in EU countries: labour market mobility, entry and exit [PDF]

open access: yes
This paper looks at the role of part-time work in labour mobility for 11 European countries. We find some evidence of part-time work being used as a stepping stone into full-time employment, but for a small proportion of individuals (less than 5%).
Buddelmeyer, Hielke   +2 more
core  

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