Results 131 to 140 of about 6,402,525 (303)
FEBS Letters, EarlyView.Drosophila park mutants serve as a model for Parkinson's disease. We used this strain to investigate the connection between oxidative stress and the circadian clock mechanism. We showed that increased oxidative stress affects the physiology of pacemaker cells, disrupting their daily structural plasticity. Lack of rhythmic signaling from pacemaker cells
Kamila Zientara +3 more
wiley +1 more source
Employment policy and the regulation of part-time work in the European Union: a comparative analysis
, 2004 This book originates from the research project 'New discourses in labour law' held at the European University Institute. A detailed analysis of part-time work regulation is presented for seven European countries, in order to ascertain how internal ...
core +1 more source
Design and analysis strategies for robust microbiome ageing research
FEBS Letters, EarlyView.The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik +5 more
wiley +1 more source
Informal Forms of Work and the Fragmentation of Local Labour Markets: The Case of Part–Time Work in Greece [PDF]
Employment facts constantly change. It is a common ascertainment among a large portion of researchers that changes in productive and regulatory patterns are followed by an expansion of informal and flexible forms of work.
Stelios Gialis
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Does part-time work at school impact on going to university? [PDF]
, 2012 Combining school study with part-time or casual work is an increasing trend for Australian high school students. For some, it is a way of earning some extra cash and having a bit of freedom from their parents, or it is an opportunity to get some ...
Cassells, R., Gong, X., Duncan, Alan
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FEBS Letters, EarlyView.CT10 regulator of kinase (CRK) and CRK‐Like (CRKL) are signaling adaptors driving cell adhesion, motility, differentiation, and proliferation. SH2‐domain containing (SH) proteins are enriched in YXXP motifs which when phosphorylated create preferred binding sites for CRK family SH2 domains.
Phoebe M. Cousens +8 more
wiley +1 more source
Career Development of College Students through Part-Time Work: The Role of Leader-Member Exchange and Taking Charge Behavior [PDF]
This study examines the potential benefit of college students' part-time work on their career development by focusing on leader-member exchange (LMX) and taking charge behavior in the workplace.
Tomoki Sekiguchi
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FEBS Letters, EarlyView.Protein aggregates threaten proteostasis and cell health. In human cells, Hsp70–J‐domain protein‐based disaggregases remove aggregates, but how they assemble remains unclear. Our biochemical findings show that DNAJA2‐ and DNAJB1‐containing disaggregase scaffolds enhance luciferase aggregate targeting, and that Hsp70 recruitment by both J‐domain ...
Anna Szlachcic, Nadinath B. Nillegoda
wiley +1 more source
Reconstructing enzyme evolution by protein engineering
FEBS Letters, EarlyView.Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler +2 more
wiley +1 more source
Earning and learning: educational policy and the growth of part-time work by full-time pupils [PDF]
The ‘traditional’ view, in both educational and labour-market policy, of the transition from education to employment centres on the school-leaving decision — in other words, on a particular point in time when the individual concerned decides to leave ...
John Mickelwright +3 more
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