Results 101 to 110 of about 14,854 (254)

Full‐Body AI Agent: A Perspective on Multi‐Scale Collaborative AI for Systemic Biology and Precision Medicine

open access: yesAdvanced Science, EarlyView.
We propose the Full‐Body AI Agent, a multi‐scale collaborative framework with 7 biological‐layer agents. It unifies multi‐omics/clinical data via standardized protocols, enabling phenotype‐guided closed‐loop reasoning, quantitative evaluation, and LLM safeguards, with promising applications in tumor metastasis modeling and precision drug development ...
Aoqi Wang   +11 more
wiley   +1 more source

Partial Ambiguity Resolution Strategy for Single-Frequency GNSS RTK/INS Tightly Coupled Integration in Urban Environments

open access: yes
Single-frequency global navigation satellite system/inertial navigation system (GNSS/INS) integration has wide application prospects in urban environments; however, correct integer ambiguity is the major challenge because of GNSS-blocked environments. In
Xiqi Wang   +3 more
core   +1 more source

A Bioinspired Three‐Dimensional High‐Curvature Nano‐Interface Integrated Microfluidic Chip for Small Extracellular Vesicles Enrichment and Machine Learning‐Assisted Prostate Cancer Precision Diagnosis

open access: yesAdvanced Science, EarlyView.
A biotin‐modified artificial insertion peptide functionalized three‐dimensional high‐curvature‐TiO2 nano‐interface was engineered in a microfluidic chip to improve the isolation efficiency of small extracellular vesicles (sEVs). This chip balanced affinity, releasability, and extendibility, enabling high‐throughput recovery of sEVs for downstream ...
Le Wang   +7 more
wiley   +1 more source

Haplotype‐Resolved 3D Genomic Landscapes and Their Impacts on Agronomic Traits in Grapevine

open access: yesAdvanced Science, EarlyView.
This study presents a haplotype‐resolved 3D genomic landscape of grapevine, revealing that structural variations (SVs) are closely associated with phased topologically associating domain (TAD) boundary transitions. These rearrangements coordinate with allele‐specific DNA methylation (ASM) and allele‐biased gene expression (ASE) to shape key agronomic ...
Yanling Peng   +18 more
wiley   +1 more source

Performance of precise marine positioning using future modernised global satellite positioning systems and a novel partial ambiguity resolution technique

open access: yes, 2009
The International Maritime Organisation (IMO) established a set of positioning requirements for future Global Navigation Satellite System (GNSS) constellations in IMO resolution A.915.
Parkins, A.J.
core  

Foundations of continuous-time recursive utility : differentiability and normalization of certainty equivalents [PDF]

open access: yes, 2009
This paper relates recursive utility in continuous time to its discrete-time origins and provides a rigorous and intuitive alternative to a heuristic approach presented in [Duffie, Epstein 1992], who formally define recursive utility in continuous time ...
Seifried, Frank Thomas, Kraft, Holger
core  

Mapping the “Supply–Demand–Flow” of Ecosystem Services for Ecosystem Management in China

open access: yesAdvanced Science, EarlyView.
This study develops a “supply–demand–flow” framework clarifies how ecosystem services move between regions by distinguishing potential and actual supply and demand. Using integrated biophysical–socioeconomic modeling, nine services in China were mapped.
Yikun Zhang   +3 more
wiley   +1 more source

Dynamic decision making under ambiguity : a portfolio choice experiment [PDF]

open access: yes, 2016
Neoclassical economic theory assumes that when agents tackle dynamic decisions under ambiguity, preferences are represented by Expected Utility and prior beliefs are updated according to Bayes rule, upon the arrival of partial information.
Georgalos, Konstantinos
core  

Traction Force Microscopy for Viscoelastic Substrates: A Semi‐Analytical Method

open access: yesAdvanced Science, EarlyView.
A semi‐analytical viscoelastic traction force microscopy framework is introduced for quantifying time‐resolved cell tractions on flat finite‐thickness substrates. The method generalizes elastic traction force microscopy to Generalized Maxwell materials, identifies when elastic approximations remain valid and, when they do not, shows that inferred ...
Adrià Villacrosa‐Ribas   +10 more
wiley   +1 more source

The impact of new signals on precise marine navigation - initial results from an experiment in Harwich Harbour

open access: yes, 2008
The General Lighthouse Authorities of the United Kingdom and Ireland (GLAs) are supporting a project at University College London (UCL) to study whether it is possible to meet the International Maritime Organisation’s (IMO) future requirements for port ...
Grant, A, Cross, PA, Parkins, AJ
core  

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