Results 81 to 90 of about 448,559 (305)

Diversity and complexity in neural organoids

open access: yesFEBS Letters, EarlyView.
Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley   +1 more source

Comparative studies on biosynthesis, partial characterization of silver nanoparticles and antimicrobial activities in some edible mushroom

open access: yes, 2016
Microbial silver nanoparticles have been known to have bactericidal effects but the antimicrobial mechanism have not been clearly revealed. The use of microorganisms in the synthesis of nanoparticles emerges as an eco-​friendly approach.
Chandan, N.   +2 more
core  

Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation

open access: yesFEBS Letters, EarlyView.
Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz   +11 more
wiley   +1 more source

Linking neurogenesis, oligodendrogenesis, and myelination defects to neurodevelopmental disruption in primary mitochondrial disorders

open access: yesFEBS Letters, EarlyView.
Mitochondrial remodeling shapes neural and glial lineage progression by matching metabolic supply with demand. Elevated OXPHOS supports differentiation and myelin formation, while myelin compaction lowers mitochondrial dependence, revealing mitochondria as key drivers of developmental energy adaptation.
Sahitya Ranjan Biswas   +3 more
wiley   +1 more source

An isoform of 14‐3‐3 protein regulates transbilayer lipid movement at the plasma membrane

open access: yesFEBS Letters, EarlyView.
Loss of 14‐3‐3ζ in CHO cells confers resistance to exogenous phosphatidylserine (PS) and impairs endocytosis‐independent inward flip‐flop of fluorescent PS at the plasma membrane. RNAi‐mediated knockdown reproduces this defect, while no additive effect is seen in ATP11C‐deficient cells.
Akiko Yamaji‐Hasegawa   +3 more
wiley   +1 more source

Linear codes meeting the Griesmer bound, minihypers and geometric applications

open access: yesLe Matematiche, 2004
Coding theory and Galois geometries are two research areas which greatly influence each other. In this talk, we focus on the link between linear codes meeting the Griesmer bound and minihypers in finite projective spaces.
Leo Storme
doaj  

A partial characterization of clique graphs

open access: yes, 1968
A partial characterization of clique graphs is given here, including a method for constructing a graph having a given graph as its clique graph, provided the given graph meets certain conditions. In addition, an example is presented to show the existence
Hamelink, Ronald C.
core   +1 more source

Epigenetic blind spots – the role of DNA methylation dynamics in stem cell‐based models of embryogenesis

open access: yesFEBS Letters, EarlyView.
Embryo‐like structures (stembryos) are an innovative tool, but they are hindered by experimental variability and limited developmental potential. DNA methylation is crucial for mammalian development, but its status in stembryo models is poorly characterized.
Sara Canil   +4 more
wiley   +1 more source

Combinatorial Designs with Two Singular Values II. Partial Geometric Designs

open access: yes
In this and an earlier paper [17] we study combinatorial designs whose incidence matrix has two distinct singular values.These generalize (v, k, ë) designs, and include uniform multiplicative designs and partial geometric designs.Here we study the latter,
Spence, E., Dam, E.R. van
core   +2 more sources

Partially-honest Nash implementation: Characterization results [PDF]

open access: yes
This paper studies implementation problems in the wake of a recent trend of implementation of non-consequentialist nature, which draws on the evidence taken from experimental and behavioral economics.
Yoshihara, Naoki, Lombardi, Michele
core  

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