Results 61 to 70 of about 680,986 (287)

Structural instability impairs function of the UDP‐xylose synthase 1 Ile181Asn variant associated with short‐stature genetic syndrome in humans

open access: yesFEBS Letters, EarlyView.
The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li   +2 more
wiley   +1 more source

Excel implementation of finite difference methods for option pricing

open access: yesSpreadsheets in Education, 2016
This paper presents and explains finite difference methods for pricing options and shows how these methods may be implemented in Excel. We cover both the explicit and the implicit finite difference methods.
Timothy J Kyng   +2 more
doaj  

An efficient numerical scheme for the study of equal width equation

open access: yesResults in Physics, 2018
In this work a new numerical scheme is proposed in which Haar wavelet method is coupled with finite difference scheme for the solution of a nonlinear partial differential equation.
Abdul Ghafoor, Sirajul Haq
doaj   +1 more source

Holistic projection of initial conditions onto a finite difference approximation

open access: yes, 2001
Modern dynamical systems theory has previously had little to say about finite difference and finite element approximations of partial differential equations (Archilla, 1998).
A.J Roberts   +4 more
core   +1 more source

Solutions of several general quadratic partial differential-difference equations in ℂ2

open access: yesDemonstratio Mathematica
Abstract In this article, we have introduced general transformation to solving the general quadratic equations. It is of interest to know about the existence and form of the solutions of general quadratic functional equations. By utilizing Nevanlinna theory for several complex variables and the transformation, we study the existence and ...
Ahamed Molla Basir, Mandal Sanju
openaire   +2 more sources

Cell wall target fragment discovery using a low‐cost, minimal fragment library

open access: yesFEBS Letters, EarlyView.
LoCoFrag100 is a fragment library made up of 100 different compounds. Similarity between the fragments is minimized and 10 different fragments are mixed into a single cocktail, which is soaked to protein crystals. These crystals are analysed by X‐ray crystallography, revealing the binding modes of the bound fragment ligands.
Kaizhou Yan   +5 more
wiley   +1 more source

Solutions of fractional order pseudo-hyperbolic telegraph partial differential equations using finite difference method

open access: yesAlexandria Engineering Journal, 2022
In this study, the explicit finite difference method is used to solve the fractional-order pseudo-hyperbolic telegraph partial differential equation by means of Caputo fractional derivative.
Sadeq Taha Abdulazeez, Mahmut Modanli
doaj   +1 more source

Solutions of certain Fermat-type partial differential-difference equations

open access: yes
The purpose of this paper is to investigate the non-constant entire as well as meromorphic solutions of the Fermat-type partial differential-difference equation: \[\left(\sum_{j=1}^m\frac{\partial f(z_1, z_2, \ldots, z_m)}{\partial z_j}\right)^{m_1} + f^{m_2}(z_1 + c_1, z_2 + c_2, \ldots, z_m + c_m ) = 1,\] where $m_1$ and $m_2$ are positive integers ...
Majumder, Sujoy, Pramanik, Debabrata
openaire   +2 more sources

Organ‐specific redox imbalances in spinal muscular atrophy mice are partially rescued by SMN antisense oligonucleotides

open access: yesFEBS Letters, EarlyView.
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley   +1 more source

Convergence of a finite difference scheme to weak solutions of the system of partial differential equation arising in mean field games [PDF]

open access: yes, 2015
Mean field type models describing the limiting behavior of stochastic differential games as the number of players tends to +$\infty$, have been recently introduced by J-M. Lasry and P-L. Lions.
Achdou, Yves, Porretta, Alessio
core   +2 more sources

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