Results 71 to 80 of about 6,829,605 (274)
FEBS Letters, EarlyView.Obesity raises blood levels of PAI‐1, a protein linked to metabolic dysfunction‐associated steatotic liver disease in people with obesity. In female mice fed a high‐fat diet, partially lowering PAI‐1 led to smaller subcutaneous fat cells and lower liver cholesterol, without changing body weight or insulin sensitivity.
Claudia E. Ramirez Bustamante +10 more
wiley +1 more source
Solutions of certain Fermat-type partial differential-difference equations
The purpose of this paper is to investigate the non-constant entire as well as meromorphic solutions of the Fermat-type partial differential-difference equation: \[\left(\sum_{j=1}^m\frac{\partial f(z_1, z_2, \ldots, z_m)}{\partial z_j}\right)^{m_1} + f^{m_2}(z_1 + c_1, z_2 + c_2, \ldots, z_m + c_m ) = 1,\] where $m_1$ and $m_2$ are positive integers ...
Majumder, Sujoy, Pramanik, Debabrata
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Emerging experimental and computational methods for studying redox‐regulated structural transitions
FEBS Letters, EarlyView.Redox reactions can reshape proteins and alter how they behave in cells, with important consequences for health and disease. This review explores emerging experimental and computational approaches for discovering these redox‐sensitive protein switches, revealing their structural effects, and predicting their behavior, opening new opportunities to ...
Tasneem Rass +2 more
wiley +1 more source
Solutions of several general quadratic partial differential-difference equations in ℂ 2
Demonstratio MathematicaAbstract In this article, we have introduced general transformation to solving the general quadratic equations. It is of interest to know about the existence and form of the solutions of general quadratic functional equations.
Ahamed Molla Basir, Mandal Sanju
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Synergistic perspectives—How single‐molecule biophysics complement biochemical understanding
FEBS Letters, EarlyView.In this review, we discuss how ensemble biochemistry and single‐molecule approaches are complementary, outline commonly used single‐molecule techniques, and illustrate their relevance through two representative case studies: chromatin organization by SMC complexes and pathway choice during DNA double‐strand break repair.
Sara De Bragança +2 more
wiley +1 more source
INTEGRAL METHODS FOR DESCRIBING PULSATILE FLOW
Acta Polytechnica, 2016 This paper presents an approximate solution of the pulsatile flow of a Newtonian fluid in the laminar flow regime in a rigid tube of constant diameter. The model is represented by two ordinary differential equations. The first equation describes the time
David Hromadka +2 more
doaj +1 more source
Structural and biochemical analysis of a B12 superbinder
FEBS Letters, EarlyView.BtuG proteins are vitamin B12 scavengers in Bacteroides thetaiotaomicron, a dominant human gut bacterium. We present crystal structures of three BtuG homologs bound to cobalamin and its precursor cobinamide, revealing picomolar binding affinities, among the highest known for any natural protein.
Jose M. Martinez Felices +3 more
wiley +1 more source
Forms of entire solutions of partial differential difference equations with constant coefficients
Electronic Journal of Differential EquationsThe purpose of this article is to describe the transcendental entire solutions of quadratic trinomial partial differential equations (PDDEs) with constant coefficients. We establish theorems on the forms of finite order transcendental entire solutions for such PDDEs, which generalize and improve previous theorems.
Xin Ding, Xiu Min Zheng
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FEBS Letters, EarlyView.Mycobacterial 3‐methylcrotonyl‐CoA carboxylase uses a mobile biotin‐carrying domain to shuttle a carboxyl group between two catalytic sites, enabling carboxylation of 3‐methylcrotonyl‐CoA during leucine breakdown. Cryo‐electron microscopy captures the carrier at both sites and reveals an inward loop movement that may prevent futile rebinding to the ...
Ajit Yadav +2 more
wiley +1 more source
Discrete Dynamics in Nature and Society, 2012 The numerical and analytic solutions of the mixed problem for multidimensional fractional hyperbolic partial differential equations with the Neumann condition are presented. The stable difference scheme for the numerical solution of the mixed problem for
Allaberen Ashyralyev, Fadime Dal
doaj +1 more source