Results 101 to 110 of about 1,497,624 (355)

A synthetic benzoxazine dimer derivative targets c‐Myc to inhibit colorectal cancer progression

Molecular Oncology, EarlyView.
Benzoxazine dimer derivatives bind to the bHLH‐LZ region of c‐Myc, disrupting c‐Myc/MAX complexes, which are evaluated from SAR analysis. This increases ubiquitination and reduces cellular c‐Myc. Impairing DNA repair mechanisms is shown through proteomic analysis.
Nicharat Sriratanasak, Bodee Nutho, Worawat Wattanathana, Narumon Phaonakrop, Bunnatut Panasawatwong, Katharina Erlenbach‐Wuensch, Sittiruk Roytrakul, Regine Schneider‐Stock, Pithi Chanvorachote   +8 more
wiley   +1 more source

Software for the numerical solution of first-order partial differential equations

Discrete and Continuous Models and Applied Computational Science, 2019
Partial differential equations of the first order, arising in applied problems of optics and optoelectronics, often contain coefficients that are not defined by a single analytical expression in the entire considered domain.
Yaroslav Yu Kuziv
doaj   +1 more source

Solution of Non-Linear Partial Differential Equations Using Laplace Transform Modified Adomian Decomposition Method

, 2022
Parmeshwari V. Aland, Prince Singh
openalex   +1 more source

Tumor and germline testing with next generation sequencing in epithelial ovarian cancer: a prospective paired comparison using an 18‐gene panel

Molecular Oncology, EarlyView.
Genetic testing in epithelial ovarian cancer includes both germline and tumor‐testing. This approach often duplicates resources. The current prospective study assessed the feasibility of tumor‐first multigene testing by comparing tumor tissue with germline testing of peripheral blood using an 18‐gene NGS panel in 106 patients.
Elisabeth Spenard, Cristina Mitric, Melanie Care, Tracy L. Stockley, Raymond H. Kim, Jeanna McCuaig, Blaise Clarke, Laura Ranich, Clare Sheen, Sarah E. Ferguson, Liat Hogen, Taymaa May, Marcus Q. Bernardini   +12 more
wiley   +1 more source

Projected iterations of fixed point type to solve nonlinear partial Volterra integro--differential equations [PDF]

, 2020
M. Berenguer, D. Gámez
openalex   +1 more source

Construction of complex solutions to nonlinear partial differential equations using simpler solutions [PDF]

, 2021
А. В. Аксенов, Andrei D. Polyanin   +1 more
openalex   +1 more source

Glycosylated LGALS3BP is highly secreted by bladder cancer cells and represents a novel urinary disease biomarker

Molecular Oncology, EarlyView.
Urinary LGALS3BP is elevated in bladder cancer patients compared to healthy controls as detected by the 1959 antibody–based ELISA. The antibody shows enhanced reactivity to the high‐mannose glycosylated variant secreted by cancer cells treated with kifunensine (KIF).
Asia Pece, Giulio Lovato, Ilaria Cela, Arianna Mercatelli, Benedetta Ferro, Jussi Nikkola, Sara Pagotto, Tommaso Grottola, Vincenzo De Laurenzi, Rossella Cicchetti, Antonio Marchetti, Luigi Schips, Rossano Lattanzio, Stefano Iacobelli, Emily Capone, Peter Black, Mads Daugaard, Michele Marchioni, Gianluca Sala   +18 more
wiley   +1 more source

Investigation of solution behavior of Differential Equations by Sumudu methods of random complex Partial Differential Equations

Cumhuriyet Science Journal
In this study, solutions of random complex partial differential equations were found using the two-dimensional Sumudu transformation method(STM).
Mehmet Merdan, Merve Merdan, Rıdvan Şahin   +2 more
doaj   +1 more source

The Extended Trial Equation Method for Some Time Fractional Differential Equations

Discrete Dynamics in Nature and Society, 2013
Nonlinear fractional partial differential equations have been solved with the help of the extended trial equation method. Based on the fractional derivative in the sense of modified Riemann-Liouville derivative and traveling wave transformation, the ...
Yusuf Pandir, Yusuf Gurefe, Emine Misirli   +2 more
doaj   +1 more source

CDK11 inhibition induces cytoplasmic p21WAF1 splice variant by p53 stabilisation and SF3B1 inactivation

Molecular Oncology, EarlyView.
CDK11 inhibition stabilises the tumour suppressor p53 and triggers the production of an alternative p21WAF1 splice variant p21L, through the inactivation of the spliceosomal protein SF3B1. Unlike the canonical p21WAF1 protein, p21L is localised in the cytoplasm and has reduced cell cycle‐blocking activity.
Radovan Krejcir, Lukasz Arcimowicz, Lucia Martinkova, Vaclav Hrabal, Filip Zavadil Kokas, Tomas Henek, Martina Kucerikova, Ondrej Bonczek, Pavlina Zatloukalova, Lenka Hernychova, Philip J. Coates, Borivoj Vojtesek, David P. Lane   +12 more
wiley   +1 more source