Results 91 to 100 of about 3,532,407 (279)

DeepDefend: A comprehensive framework for DDoS attack detection and prevention in cloud computing

Journal of King Saud University: Computer and Information Sciences
DeepDefend is an advanced framework for real-time detection and prevention of DDoS attacks in cloud environments. It employs deep learning techniques, notably CNN-LSTM-Transformer networks, to predict network traffic entropy and detect potential attacks.
Mohamed Ouhssini, Karim Afdel, Elhafed Agherrabi, Mohamed Akouhar, Abdallah Abarda   +4 more
doaj   +1 more source

Statistical inference for partial differential equations*

ESAIM: Proceedings and Surveys, 2014
Many physical phenomena are modeled by parametrized PDEs. The poor knowledge on the involved parameters is often one of the numerous sources of uncertainties on these models.
Grenier Emmanuel, Hoffmann Marc, Lelièvre Tony, Louvet Violaine, Prieur Clémentine, Rachdi Nabil, Vigneaux Paul   +6 more
doaj   +1 more source

Finding novel vulnerabilities of hypomorphic BRCA1 alleles

Molecular Oncology, EarlyView.
Synthetic lethality screens performed to identify novel vulnerabilities often model complete gene loss, thereby overlooking patient‐derived hypomorphic mutations. In this study, we have performed genome‐wide CRISPR screens on BRCA1 hypomorphic mutations, showing BRCA1I26A behaves like wild‐type, while BRCA1R1699Q mimics deficiency. Furthermore, we have
Anne Schreuder, Klaas de Lint, Hồ Mỹ Phúc Võ, Mariana M. Góis, Rosalie A. Kampen, Marta San Martin Alonso, Ilse Nootenboom, Veronica Garzero, Tiemen J. Wendel, Rob M. F. Wolthuis, Sylvie M. Noordermeer   +10 more
wiley   +1 more source

Advancements in detecting, preventing, and mitigating DDoS attacks in cloud environments: A comprehensive systematic review of state-of-the-art approaches

Egyptian Informatics Journal
This comprehensive study examines cutting-edge strategies for combating Distributed Denial of Service (DDoS) attacks in cloud environments, addressing a critical gap in recent literature. Through a systematic review of the latest advancements, we propose
Mohamed Ouhssini, Karim Afdel, Mohamed Akouhar, Elhafed Agherrabi, Abdallah Abarda   +4 more
doaj   +1 more source

A novel quinazolinone insulin receptor inhibitor and its synergy with an EGFR inhibitor in glucose‐driven glioblastoma

Molecular Oncology, EarlyView.
The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka, Wioleta Cieślik, Wojciech Płaziński, Katarzyna Stępnik, Anna Boguszewska‐Czubara, Elżbieta Kot, Robert Musioł, Mateusz Jasica, Anna Mrozek‐Wilczkiewicz, Katarzyna Malarz   +9 more
wiley   +1 more source

Extrapolation techniques for first order hyperbolic partial differential equations [PDF]

, 1980
A uniform grid of step size h is superimposed on the space variable x in the first order hyperbolic partial differential equation ∂u/∂t + a ∂u/∂x = 0 (a > 0, x > 0, t > 0).
Twizell, E H
core   +3 more sources

Dynamics of cell growth: Exponential growth and division after a minimum cell size

Partial Differential Equations in Applied Mathematics
In this paper, we consider a mathematical model for cell division using a Pantograph-type nonlocal partial differential equation, accompanied by relevant initial and boundary conditions. This formulation results in a nonlocal singular eigenvalue problem.
M. Mohsin, A.A. Zaidi, B. van Brunt
doaj   +1 more source

Partial differential equations with piecewise constant delay

International Journal of Mathematics and Mathematical Sciences, 1991
The influence of certain discontinuous delays on the behavior of solutions to partial differential equations is studied. In Section 2, the initial value problems (IVP) are discussed for differential equations with piecewise constant argument (EPCA) in ...
Joseph Wiener, Lokenath Debnath
doaj   +1 more source

A Complete Equational Axiomatisation of Partial Differentiation

Electronic Notes in Theoretical Computer Science, 2020
We formalise the well-known rules of partial differentiation in a version of equational logic with function variables and binding constructs. We prove the resulting theory is complete with respect to polynomial interpretations. The proof makes use of Severi's interpolation theorem that all multivariate Hermite problems are solvable.
openaire   +2 more sources

Loss of proton‐sensing TDAG8 increases tumor progression in mouse models of colon cancer

Molecular Oncology, EarlyView.
Loss of the pH‐sensing receptor TDAG8 accelerates colorectal cancer progression in mice. Animals lacking TDAG8 expression had increased tumor growth, DNA damage, and recruitment of tumor‐associated immune cells, including macrophages, neutrophils, and monocytes.
Ermanno Malagola, Yasmine Illi, Anna Bircher, Marijn Wilmink, Rachele F. Malagutti, Solenn Ottié, Cordelia Schuler, Pedro A. Ruiz, Cheryl de Vallière, Klaus Seuwen, Gerhard Rogler, Martin Hausmann   +11 more
wiley   +1 more source