Results 81 to 90 of about 60,411 (268)

AscF in the mycobacterial CIII–CIV supercomplex lacks metal and nucleotide binding but links malate oxidation to respiration

FEBS Letters, EarlyView.
The mycobacterial CIII‐CIV respiratory supercomplex is an obligate assembly, encompassing several subunits of unknown functions. We have characterized the intracellular subunit AscF, and show that it is unlikely to be a sensor for metals or nucleotides, but is required for growth on nonfermentable energy sources, and likely works as an adapter for ...
Eni Rile, Riccardo Diamanti, Daniel Lundin, Soni Sharma, Robin Lissner, Coenraad P. Kuil, Martin Högbom, Dirk Bald, Dan Sjöstrand   +8 more
wiley   +1 more source

Dynamics of cell growth: Exponential growth and division after a minimum cell size

Partial Differential Equations in Applied Mathematics
In this paper, we consider a mathematical model for cell division using a Pantograph-type nonlocal partial differential equation, accompanied by relevant initial and boundary conditions. This formulation results in a nonlocal singular eigenvalue problem.
M. Mohsin, A.A. Zaidi, B. van Brunt
doaj   +1 more source

A Complete Equational Axiomatisation of Partial Differentiation

Electronic Notes in Theoretical Computer Science, 2020
We formalise the well-known rules of partial differentiation in a version of equational logic with function variables and binding constructs. We prove the resulting theory is complete with respect to polynomial interpretations. The proof makes use of Severi's interpolation theorem that all multivariate Hermite problems are solvable.
openaire   +2 more sources

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

Molecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Stability of an additive-quadratic functional equation in modular spaces

Open Mathematics
Using the direct method, we prove the Hyers-Ulam-Rassias stability of the following functional equation: ϕ(x+y,z+w)+ϕ(x−y,z−w)−2ϕ(x,z)−2ϕ(x,w)=0\phi \left(x+y,z+w)+\phi \left(x-y,z-w)-2\phi \left(x,z)-2\phi \left(x,w)=0 in ρ\rho -complete convex modular ...
Baza Abderrahman, Rossafi Mohamed, Park Choonkil, Donganont Mana   +3 more
doaj   +1 more source

Solutions of a Certain Partial Differential Equation [PDF]

Proceedings of the National Academy of Sciences, 1931
The partial differential equation ∂u/∂t = x(∂^2u/∂x^2 – u) is readily seen to possess the two particular solutions U1 = xe^(-x tanh t) sech^2t, U2 = e^(-x coth t).
openaire   +2 more sources

EDNRB‐dependent endothelin signaling reduces proliferation and promotes proneural‐to‐mesenchymal transition in gliomas

Molecular Oncology, EarlyView.
Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau, Leonor Garcia, Hugo Arnold, Antonija Hanžek, Maialen Arrieta, Laurent R Gauthier, Christine Granotier‐Beckers, François D Boussin, Amaury Herbet, Marie Hautière, Valentin Asei‐Ceschino, Clémentin Jacques, Laura Brard, Thomas Harnois, Valérie Coronas, Bruno Constantin, Aurélien Chatelier, Jean Chemin, Serge Urbach, Martial Seveno, Szimonetta Hideg, Chantal Ripoll, Kasandra Aguilar‐Cázarez, Min Zheng, Guo‐Hao Huang, Sheng‐Qing Lv, Lei Zhang, Philippe Rondard, Laurent Prezeau, Jean‐Philippe Pin, Hugues Duffau, Luc Bauchet, Valérie Rigau, Franck Denat, Charles Truillet, Didier Boquet, Jean‐Philippe Hugnot   +36 more
wiley   +1 more source

CD47 promotes mitogen‐activated protein kinase and epithelial‐to‐mesenchymal transition molecular programs to drive prometastatic phenotypes in non‐small cell lung cancer

Molecular Oncology, EarlyView.
Beyond its role in immune evasion, this study identified that CD47 drives tumor‐intrinsic signaling in non‐small cell lung cancer (NSCLC). Transcriptomic profiling and functional studies revealed that CD47 regulates cell adhesion, migration, and metastasis through an ERK–EMT signaling axis.
Asa P.Y. Lau, Lilian G. Zhai, Ryunosuke Hoshi, Zackary Rousseau, Abraam Zakhary, Yin Fang Wu, Rola M. Saleeb, Heyu Ni, Kelsie L. Thu   +8 more
wiley   +1 more source

Heterozygous loss‐of‐function alleles associate the conserved 3′‐5′ exoribonuclease EXOSC10 with hypersensitivity to the anticancer drug 5‐fluorouracil

Molecular Oncology, EarlyView.
EXOSC10, an essential nuclear RNA exosome‐associated 3′‐5′ exoribonuclease, is inhibited by the anticancer drug 5‐fluorouracil (5‐FU), and EXOSC10 depletion increases 5‐FU sensitivity. The colon‐cancer variant EXOSC10S402T, located in a proteolysis motif, is stable and nuclear but nonfunctional in vivo.
Radhika Sain, Yann Le Page, Frédéric Percevault, Emmanuelle Becker, Luc Negroni, Almudena Fernandez, Marta Cantero, Diego Muñoz‐Santos, Lluís Montoliu, Cyrille Garnier, Michael Primig   +10 more
wiley   +1 more source

Partial differential equations. An outline

Computers & Mathematics with Applications
This is a chart which may serve as an outline of classification, solution and examples for partial differential equations.
openaire   +1 more source