Results 71 to 80 of about 752,725 (275)

Strong-viscosity Solutions: Semilinear Parabolic PDEs and Path-dependent PDEs

open access: yes, 2019
The aim of the present work is the introduction of a viscosity type solution, called strong-viscosity solution to distinguish it from the classical one, with the following peculiarities: it is a purely analytic object; it can be easily adapted to more ...
Cosso, Andrea, Russo, Francesco
core  

LDAcoop: Integrating non‐linear population dynamics into the analysis of clonogenic growth in vitro

open access: yesMolecular Oncology, EarlyView.
Limiting dilution assays (LDAs) quantify clonogenic growth by seeding serial dilutions of cells and scoring wells for colony formation. The fraction of negative wells is plotted against cells seeded and analyzed using the non‐linear modeling of LDAcoop.
Nikko Brix   +13 more
wiley   +1 more source

ON SINGULAR SOLUTIONS OF CLAIRAUT EQUATIONS IN THE THEORY OF ORDINARY DIFFERENTIAL AND PARTIAL DERIVATIVE EQUATIONS

open access: yesИзвестия высших учебных заведений. Поволжский регион: Физико-математические науки, 2020
Background. There is no problem in finding a general solution to the ordinary differential Clairaut equation. The corresponding procedure is described in details in the theory of ordinary differential equations.
L. A. Zhidova
doaj   +1 more source

Infrared laser sampling of low volumes combined with shotgun lipidomics reveals lipid markers in palatine tonsil carcinoma

open access: yesMolecular Oncology, EarlyView.
Nanosecond infrared laser (NIRL) low‐volume sampling combined with shotgun lipidomics uncovers distinct lipidome alterations in oropharyngeal squamous cell carcinoma (OPSCC) of the palatine tonsil. Several lipid species consistently differentiate tumor from healthy tissue, highlighting their potential as diagnostic markers.
Leonard Kerkhoff   +11 more
wiley   +1 more source

Global solutions for bi-harmonic inhomogeneous non-linear Schrödinger equations in Lebesgue spaces

open access: yesJournal of Inequalities and Applications
This paper studies the inhomogeneous bi-harmonic nonlinear Schrödinger equation i u ˙ + Δ 2 u ± | x | − τ | u | p − 1 u = 0 , $$ \mbox{i}\dot{u} +\Delta ^{2} u\pm |x|^{-\tau}|u|^{p-1}u=0, $$ where u : = u ( t , x ) : R × R N → C $u:=u(t,x):\mathbb{R ...
Radhia Ghanmi   +2 more
doaj   +1 more source

Recurrent cancer‐associated ERBB4 mutations are transforming and confer resistance to targeted therapies

open access: yesMolecular Oncology, EarlyView.
We show that the majority of the 18 analyzed recurrent cancer‐associated ERBB4 mutations are transforming. The most potent mutations are activating, co‐operate with other ERBB receptors, and are sensitive to pan‐ERBB inhibitors. Activating ERBB4 mutations also promote therapy resistance in EGFR‐mutant lung cancer.
Veera K. Ojala   +15 more
wiley   +1 more source

Inhomogeneous Schrödinger system with inverse square potential in three space dimensions

open access: yesJournal of Inequalities and Applications
This work studies the inhomogeneous Schrödinger coupled system with inverse square potential i ∂ t u j + Δ u j − λ | x | 2 u j = ± | x | − τ ( ∑ k = 1 m a j k | u k | p ) | u j | p − 2 u j . $$ i\partial _{t} u_{j} +\Delta u_{j}-\frac{\lambda}{|x|^{2}}u_{
Salah Boulaaras   +2 more
doaj   +1 more source

Peroxidasin enables melanoma immune escape by inhibiting natural killer cell cytotoxicity

open access: yesMolecular Oncology, EarlyView.
Peroxidasin (PXDN) is secreted by melanoma cells and binds the NK cell receptor NKG2D, thereby suppressing NK cell activation and cytotoxicity. PXDN depletion restores NKG2D signaling and enables effective NK cell–mediated melanoma killing. These findings identify PXDN as a previously unrecognized immune evasion factor and a potential target to improve
Hsu‐Min Sung   +17 more
wiley   +1 more source

Crucial parameters for precise copy number variation detection in formalin‐fixed paraffin‐embedded solid cancer samples

open access: yesMolecular Oncology, EarlyView.
This study shows that copy number variations (CNVs) can be reliably detected in formalin‐fixed paraffin‐embedded (FFPE) solid cancer samples using ultra‐low‐pass whole‐genome sequencing, provided that key (pre)‐analytical parameters are optimized.
Hanne Goris   +10 more
wiley   +1 more source

A Method for Image Decontamination Based on Partial Differential Equation

open access: yesMATEC Web of Conferences, 2015
This paper will introduce the method to apply partial differential equations for the decontamination processing of images. It will establish continuous partial differential mathematical models for image information and use specific solving methods to ...
Hou Junping
doaj   +1 more source

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