Results 51 to 60 of about 60,411 (268)

Transparent DDoS defense by combining Kolmogorov–Arnold networks and XAI for real-time protection in cloud environments

open access: yesTelematics and Informatics Reports
Cloud computing environments face persistent threats from sophisticated Distributed Denial of Service (DDoS) attacks. Effective defense requires not only high accuracy but also real-time performance and transparent decision-making, a combination that ...
Mohamed Ouhssini   +6 more
doaj   +1 more source

A method for constructing a complete bifurcation picture of a boundary value problem for nonlinear partial differential equations: application of the Kolmogorov-Arnold theorem [PDF]

open access: yesИзвестия высших учебных заведений: Прикладная нелинейная динамика
The purpose of this study is to develop a numerical method for bifurcation analysis of nonlinear partial differential equations, based on the reduction of partial differential equations to ordinary ones, using the Kolmogorov-Arnold theorem.
Gromov, Vasily Alexandrovich   +4 more
doaj   +1 more source

Structural insights into an engineered feruloyl esterase with improved MHET degrading properties

open access: yesFEBS Letters, EarlyView.
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa   +5 more
wiley   +1 more source

On a linear system of differential equations

open access: yesВестник КазНУ. Серия математика, механика, информатика, 2019
The linear systems of partial differential equations of the first order with the identical main parts is considered. Аpplying the well-known relation between a normal system of ordinary differential equations and a linear system of partial differential
T. М. Aldibekov, M. M. Aldazharova
doaj   +1 more source

Diversity and complexity in neural organoids

open access: yesFEBS Letters, EarlyView.
Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley   +1 more source

Epigenetic blind spots – the role of DNA methylation dynamics in stem cell‐based models of embryogenesis

open access: yesFEBS Letters, EarlyView.
Embryo‐like structures (stembryos) are an innovative tool, but they are hindered by experimental variability and limited developmental potential. DNA methylation is crucial for mammalian development, but its status in stembryo models is poorly characterized.
Sara Canil   +4 more
wiley   +1 more source

Residual tail twisting in ascidian larvae is stabilized by asymmetric myofibrils that resist bilateral symmetry restoration

open access: yesFEBS Letters, EarlyView.
Ascidian Ciona larvae initially show strong clockwise tail twisting, which is largely corrected during development. However, a small residual twist remains. This study shows that organized helical myofibrils in tail muscles mechanically stabilize this residual asymmetry, preventing complete restoration of bilateral symmetry and revealing how embryos ...
Yuki S. Kogure   +3 more
wiley   +1 more source

A Deep Neural Network Algorithm for Semilinear Elliptic PDEs with Applications in Insurance Mathematics

open access: yesRisks, 2020
In insurance mathematics, optimal control problems over an infinite time horizon arise when computing risk measures. An example of such a risk measure is the expected discounted future dividend payments.
Stefan Kremsner   +2 more
doaj   +1 more source

Degradation mechanism of the von Willebrand factor A2 domain by nattokinase

open access: yesFEBS Letters, EarlyView.
Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto   +3 more
wiley   +1 more source

Superprocesses and Partial Differential Equations

open access: yesThe Annals of Probability, 1993
This is a survey of recent developments on measure-valued Markov processes including a number of the author's important contributions. This subject has its origins in the paper of \textit{S. Watanabe} [J. Math. Kyoto Univ. 8, 141-167 (1968; Zbl 0159.462)] in which a class of measure-valued branching processes was constructed based on a family of ...
openaire   +2 more sources

Home - About - Disclaimer - Privacy