Results 101 to 110 of about 756,333 (330)

EGFR‐STAT3 activation provides a therapeutic rationale for targeting aggressive ETV1‐positive prostate cancer

open access: yesMolecular Oncology, EarlyView.
Cotargeting EGFR and STAT3 with Erlotinib and TTI‐101 impairs both 2D and 3D growth of ETV1‐overexpressing prostate cancer cells by disrupting a self‐sustaining ETV1–EGFR positive feedback loop that promotes EGFR and STAT3 expression and phosphorylation (activation).
Elsa Gomes Paiva   +5 more
wiley   +1 more source

Advancements in detecting, preventing, and mitigating DDoS attacks in cloud environments: A comprehensive systematic review of state-of-the-art approaches

open access: yesEgyptian Informatics Journal
This comprehensive study examines cutting-edge strategies for combating Distributed Denial of Service (DDoS) attacks in cloud environments, addressing a critical gap in recent literature. Through a systematic review of the latest advancements, we propose
Mohamed Ouhssini   +4 more
doaj   +1 more source

Cytomegalovirus infection is common in prostate cancer and antiviral therapies inhibit progression in disease models

open access: yesMolecular Oncology, EarlyView.
Human cytomegalovirus infection is common in normal prostate epithelium, prostate tumor tissue, and prostate cancer cell lines. CMV promotes cell survival, proliferation, and androgen receptor signaling. Anti‐CMV pharmaceutical compounds in clinical use inhibited cell expansion in prostate cancer models in vitro and in vivo, motivating investigation ...
Johanna Classon   +13 more
wiley   +1 more source

A Method for Image Decontamination Based on Partial Differential Equation

open access: yesMATEC Web of Conferences, 2015
This paper will introduce the method to apply partial differential equations for the decontamination processing of images. It will establish continuous partial differential mathematical models for image information and use specific solving methods to ...
Hou Junping
doaj   +1 more source

β‐TrCP overexpression enhances cisplatin sensitivity by depleting BRCA1

open access: yesMolecular Oncology, EarlyView.
Low levels of β‐TrCP (Panel A) allow the accumulation of BRCA1 and CtIP, which facilitate the repair of cisplatin‐induced DNA damage via homologous recombination (HR) and promote tumor cell survival. In contrast, high β‐TrCP expression (Panel B) leads to BRCA1 and CtIP degradation, impairing HR repair, resulting in persistent DNA damage and apoptosis ...
Rocío Jiménez‐Guerrero   +8 more
wiley   +1 more source

DeepDefend: A comprehensive framework for DDoS attack detection and prevention in cloud computing

open access: yesJournal of King Saud University: Computer and Information Sciences
DeepDefend is an advanced framework for real-time detection and prevention of DDoS attacks in cloud environments. It employs deep learning techniques, notably CNN-LSTM-Transformer networks, to predict network traffic entropy and detect potential attacks.
Mohamed Ouhssini   +4 more
doaj   +1 more source

Partial differential equations with piecewise constant delay

open access: yesInternational Journal of Mathematics and Mathematical Sciences, 1991
The influence of certain discontinuous delays on the behavior of solutions to partial differential equations is studied. In Section 2, the initial value problems (IVP) are discussed for differential equations with piecewise constant argument (EPCA) in ...
Joseph Wiener, Lokenath Debnath
doaj   +1 more source

Quantum resonances and partial differential equations

open access: yes, 2002
Resonances, or scattering poles, are complex numbers which mathematically describe meta-stable states: the real part of a resonance gives the rest energy, and its imaginary part, the rate of decay of a meta-stable state.
Zworski, Maciej
core   +2 more sources

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