Results 61 to 70 of about 150,861 (308)

Learning models of plant behavior for anomaly detection and condition monitoring [PDF]

open access: yes, 2007
Providing engineers and asset managers with a too] which can diagnose faults within transformers can greatly assist decision making on such issues as maintenance, performance and safety. However, the onus has always been on personnel to accurately decide
Brown, A.J.   +5 more
core   +2 more sources

Genetic attenuation of ALDH1A1 increases metastatic potential and aggressiveness in colorectal cancer

open access: yesMolecular Oncology, EarlyView.
Aldehyde dehydrogenase 1A1 (ALDH1A1) is a cancer stem cell marker in several malignancies. We established a novel epithelial cell line from rectal adenocarcinoma with unique overexpression of this enzyme. Genetic attenuation of ALDH1A1 led to increased invasive capacity and metastatic potential, the inhibition of proliferation activity, and ultimately ...
Martina Poturnajova   +25 more
wiley   +1 more source

Experimental Verification of Partial Discharges Patterns [PDF]

open access: yes, 2016
Tato bakalářská práce se zabývá problematikou částečných výbojů. Zkoumá důvody jejich vzniku a řeší jejich působení na izolační systém elektrických strojů a kabelů.
Štolfa Radim
core  

The effects of urbanization on floods in the Austin metropolitan area, Texas [PDF]

open access: yes, 1986
This report looks at compiled data from 1956-1980 to "provide a technique for estimating the magnitude and frequency of flood-peak discharges at ungaged sites and to estimate the effects of changes in urbanization on flood peaks."The effects of ...
Gannett, David G., Veenhuis, Jack E.
core   +1 more source

IMPDH inhibition enhances cytarabine efficacy in SAMHD1‐expressing leukaemia cells via guanine nucleotide depletion

open access: yesMolecular Oncology, EarlyView.
Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla   +9 more
wiley   +1 more source

Non-intrusive partial discharges investigations on aeronautic motors [PDF]

open access: yes, 2016
The present paper reports on a study of non-electrically intrusive partial discharge investigations on an aeronautic motor. Relevancy, robustness and repeatability of partial discharge testing procedures, both on insulating materials characterization and
Abadie, Cédric   +2 more
core   +1 more source

Keratin 19 as a prognostic marker and contributing factor of metastasis and chemoresistance in high‐grade serous ovarian cancer

open access: yesMolecular Oncology, EarlyView.
Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch   +13 more
wiley   +1 more source

Establishment of a humanized patient‐derived xenograft mouse model of high‐grade serous ovarian cancer for preclinical evaluation of combination immunotherapy

open access: yesMolecular Oncology, EarlyView.
We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric   +10 more
wiley   +1 more source

Study on the Detection of Single and Dual Partial Discharge Sources in Transformers Using Fiber-Optic Ultrasonic Sensors

open access: yesPhotonics
Partial discharge is a fault that occurs at the site of insulation defects within a transformer. Dual instances of partial discharge origination discharging simultaneously embody a more intricate form of discharge, where the interaction between the ...
Feng Liu   +3 more
doaj   +1 more source

Partial Discharge Behaviour of a Protrusion in Gas-Insulated Systems under DC Voltage Stress

open access: yesEnergies, 2020
High reliability, independence from environmental conditions, and the compact design of gas-insulated systems will lead to a wide application in future high voltage direct current (HVDC) transmission systems.
Thomas Götz   +2 more
doaj   +1 more source

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