Results 101 to 110 of about 71,386 (306)

Partial epilepsy with pericentral spikes: A new familial epilepsy syndrome with evidence for linkage to chromosome 4p15

, 2002
The genetic analysis of simple Mendelian epilepsies remains a key strategy in advancing our understanding of epilepsy. in this article, we describe a new family epilepsy syndrome, partial epilepsy with pericentral spikes, which we map to chromosome 4p15.
Angelica M. Claudino, Michael R. Johnson, Farrell, F., John S. Duncan, Johnson, M. R., John Stevens, Smith, SJM, James B. Rance, Kinton, L., Rance, J. B., Mary B. Davis, Claudino, A. M., Shelagh J. M. Smith, Wood, N. W., Nicholas W. Wood, Stevens, J., Fiona Farrell, Lucy Kinton, Duncan, J. S., Davis, M. B., Sander, JWA, Josemir W. A. Sander   +21 more
core   +1 more source

Smart Nanotechnologies for Multimodal Neuromodulation and Brain Interfacing

Advanced Science, EarlyView.
Recent advances in smart nanotechnologies are expanding the toolbox for brain interfacing, from wireless neuromodulation and high‐resolution sensing to targeted delivery within the central nervous system. By combining responsive nanomaterials with bioinspired design, these platforms enable multimodal interactions with neurons and glia, while also ...
Tommaso Curiale, Marie Celine Lefevre, Alessio Carmignani, Maria Cristina Ceccarelli, Matteo Battaglini, Attilio Marino, Gianni Ciofani   +6 more
wiley   +1 more source

Magnetoelectric Nanoparticle‐Based Wireless Brain–Computer Interface: Underlying Physics and Projected Technology Pathway

Advanced Science, EarlyView.
Magnetoelectric nanoparticles (MENPs) enable fully wireless, minutely invasive neuromodulation, and potentially neural recording, by converting magnetic into electric and, conversely, electric into magnetic fields, respectively, at high spatiotemporal resolution.
Elric Zhang, Max Shotbolt, Mostafa Abdel‐Mottaleb, Shawnus Chen, Victoria Andre, Jieyuan Tian, Jonathan Shulgach, Max Murphy, Brian Noga, Ping Liang, Darcy Griffin, Douglas Weber, Marta Pardo, Salvador Pane, Sakhrat Khizroev   +14 more
wiley   +1 more source

UNC13B variants associated with partial epilepsy with favourable outcome. [PDF]

Brain, 2021
Wang J, Qiao JD, Liu XR, Liu DT, Chen YH, Wu Y, Sun Y, Yu J, Ren RN, Mei Z, Liu YX, Shi YW, Jiang M, Lin SM, He N, Li B, Bian WJ, Li BM, Yi YH, Su T, Liu HK, Gu WY, Liao WP.   +22 more
europepmc   +1 more source

Cognitive effects of adjunctive perampanel for partial-onset seizures: A randomized trial

, 2016
Objective Assess cognitive effects of adjunctive perampanel in adolescents. Methods In this double-blind study (ClinicalTrials.gov identifier: NCT01161524), patients aged 12 to
Wesnes, Keith, Jesus Eric Piña‐Garza, Haichen Yang, Meador, Kimford, Dinesh Kumar, Laurenza, Antonio, Kumar, Dinesh, Keith A. Wesnes, Yang, Haichen, Kimford J. Meador, Antonio Laurenza, Piña-Garza, Jesus Eric   +11 more
core   +1 more source

Temporal Interference Stimulation Enhances Neural Regeneration

Advanced Science, EarlyView.
Temporal interference (TI) stimulation is proposed as a non‐invasive approach to enhance neural regeneration in the deep brain. Theta‐band TI modulation selectively promotes neural progenitor cell differentiation in vitro and augments hippocampal neurogenesis in amouse model of Alzheimer's disease‐like amyloidosis.
Sofia Peressotti, Maria Garcia Garrido, Patrycja Dzialecka, Rachel Man Hoi Law, Roberto Portillo‐Lara, Bethany Geary, Elena Faillace, Shirine Merlo‐Nikpay Aslie, Marcelina Wojewska, Maria Otero‐Jimenez, Martina Genta, Luqiao Tan, Karen Duff, Javier Alegre‐Abarrategui, Rylie Green, Nir Grossmann   +15 more
wiley   +1 more source

Pattern-induced partial seizures with repetitive affectionate kissing: An unusual manifestation of right temporal lobe epilepsy

, 2005
We report a case of recurrent partial seizures that were often precipitated by looking up a flight of stairs and included spitting as well as repetitive affectionate kissing automatisms.
Shamseddine A.N., Comair Y.G., Mikati M.A.   +2 more
core   +1 more source

Remote Magnetomechanical Neuromodulation Uncovers Therapeutic Mechanisms for Alleviating Parkinsonian Symptoms in Freely Moving Mice

Advanced Science, EarlyView.
Magnetomechanical neuromodulation using magnetic nanodiscs enables remote activation of neurons. In a hemiparkinsonian mouse model, alternating magnetic fields actuate the nanodiscs to generate torque that opens mechanosensitive ion channels within the subthalamic nucleus, thereby modulating basal ganglia motor circuitry.
Anouk Wolters, Lorenzo Signorelli, Christian Herff, Sophia Gimple, Renzo Riemens, Gunter Kenis, Kim Rijkers, Hamed Shabani, Jyh‐Jang Sun, Yasin Temel, Hans Clusmann, Danijela Gregurec, Sarah‐Anna Hescham   +12 more
wiley   +1 more source

Paternal Caffeine Exposure Programs Offspring Stress Vulnerability via Sperm Dlk1‐Dio3 Imprinting‐Directed Remodeling of a Novel Neural Circuit

Advanced Science, EarlyView.
The study elucidates that paternal preconception stress can drive offspring hyperresponsivity of the stress system via hypomethylation of a specific DNA region in sperm. This key link is confirmed in a cohort of prospective fathers: the epigenetic alteration is associated with elevated stress hormone levels.
Mengxi Lu, Gaole Dai, Sen Zhu, Shuai Zhang, Tingting Wang, Yuan Meng, Fang Yang, Xiaoyi Han, Hui Wang, Hao Kou, Dan Xu   +10 more
wiley   +1 more source

EFFICACY AND TOLERABILITY OF PERAMPANEL AS ADDITIONAL DRUG OF TEENAGERS WITH DRUG-RESISTANT PARTIAL EPILEPSY: RESULTS OF A RANDOMIZED DOUBLE-BLIND PLACEBO-CONTROLLED STUDY CONDUCTED IN THE RUSSIAN FEDERATION

Эпилепсия и пароксизмальные состояния, 2016
: the efficacy and tolerability of adjunctive perampanel (PER) in refractory partial epilepsy in Russian adolescents has been investigated. It was the part of three international (global) randomized placebo-controlled prospective phase III trials with ...
E. D. Belousova
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