Results 81 to 90 of about 71,386 (306)
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objectives Focal cortical dysplasia (FCD) is the most common etiology of drug‐resistant epilepsy in children. Focal to bilateral tonic–clonic seizures (FBTCS) mark a high risk of drug‐resistant epilepsy and involve thalamocortical circuitry in their generation and propagation.
Hua Xie +8 more
wiley +1 more source
Role of neurotrophins and neuropeptides in Genetic Absence Epilepsy Rats from Strasbourg (GAERS) : a model for human generalized absence seizures [PDF]
, 2010 Several studies have shown that neurotrophins and neuropeptides contribute to epileptogenesis but their impact on idiopathic generalized epilepsies is not yet elucidated.
Landweer, Svenja
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Advanced Materials Interfaces, EarlyView.Simplified quantum sensing technique for the detection of short electrical signals occurring in neuronal signaling or bioinspired technologies. We demonstrate a single frequency continuous‐wave optically detected magnetic resonance (CW‐ODMR) approach to sense signals that can be as short as 0.2 ms.
João Paulo Silva +4 more
wiley +1 more source
Targeting the PDK1/c‐Myc/SOX10 Signaling in Oligodendrocytes Alleviates Neuropathic Pain
Advanced Science, EarlyView.This work reveals that oligodendrocyte homeostasis, mediated by PDK1, is a critical determinant of neuropathic pain (NPP) pathogenesis. Disruption of PDK1 in oligodendrocytes impairs SOX10‐dependent myelination programs through c‐Myc accumulation, leading to disrupted myelination and the pathophysiology of NPP.
Pingping Qiao +7 more
wiley +1 more source
Partial and ful lown-body illusions of epileptic origin in a child with right temporoparietal epilepsy [PDF]
, 2011 Partial and full own-body illusions of neurological origin have been claimed crucial to understand the contribution of bodily experience and perception to self-consciousness.
Margitta Seeck +8 more
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Advanced Science, EarlyView.Neuronal PKM2‐driven glycolysis generates excess lactate that triggers histone H3K18 lactylation (H3K18la), establishing a pathogenic metabolic‐epigenetic axis in epilepsy. Elevated H3K18la enriches the Cop1 promoter, transcriptionally upregulating the E3 ubiquitin ligase COP1, which subsequently drives proteasomal degradation of GABAARβ2 and impairs ...
Yuan Meng +8 more
wiley +1 more source
MUSICOGENIC EPILEPSY. A REVIEW OF THE LITERATURE AND A CASE REPORT
Эпилепсия и пароксизмальные состояния, 2018 Musicogenic epilepsy is a rare form of reflex epilepsy, where seizures are triggered by listening to patient-specific sounds or music. The onset typically occurs in the adult age. In most cases of musicogenic epilepsy, the source of epileptic activity is
V. O. Generalov +4 more
doaj +1 more source
Autoimmune Encephalitis in Acute Care—Pathology, Diagnosis, and Management
Advanced Science, EarlyView.ABSTRACT Autoimmune encephalitis (AE) is characterized by immune‐mediated inflammation of the brain parenchyma, presenting with various neurological syndromes, including but not limited to seizures, altered consciousness, neuropsychiatric symptoms, and movement disorders.
Suneesh Thilak +9 more
wiley +1 more source
Antiepileptic Drug Withdrawal in Partial Epilepsy
Pediatric Neurology Briefs, 2000 The optimal time of discontinuing anticonvulsant treatment in children with cryptogenic partial epilepsy was evaluated at the Universities of Chieti and Siena, Italy.
J Gordon Millichap
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Genetic analysis of human absence epilepsy
, 2010 Idiopathic Mendelian epilepsies have been typically identified as channelopathies. Evidence suggests that mutations in genes encoding GABAA receptors, GABAB receptors or voltage-dependent calcium channels (VDCCs) may underlie childhood absence epilepsy ...
Robinson, R.A.
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