Results 101 to 110 of about 282,929 (321)

Analytic solution for the space-time fractional Klein-Gordon and coupled conformable Boussinesq equations

open access: yesResults in Physics, 2018
In this paper, we constructed a travelling wave solution for space-time fractional nonlinear partial differential equations by using the modified extended Tanh method with Riccati equation.
Muhannad A. Shallal   +2 more
doaj   +1 more source

Large‐scale bidirectional arrayed genetic screens identify OXR1 and EMC4 as modifiers of αSynuclein aggregation

open access: yesFEBS Open Bio, EarlyView.
Activation of the mitochondrial protein OXR1 increases pSyn129 αSynuclein aggregation by lowering ATP levels and altering mitochondrial membrane potential, particularly in response to MSA‐derived fibrils. In contrast, ablation of the ER protein EMC4 enhances autophagic flux and lysosomal clearance, broadly reducing α‐synuclein aggregates.
Sandesh Neupane   +11 more
wiley   +1 more source

Solving Fractional Partial Differential Equations with Corrected Fourier Series Method

open access: yesAbstract and Applied Analysis, 2014
The corrected Fourier series (CFS) is proposed for solving partial differential equations (PDEs) with fractional time derivative on a finite domain. In the previous work, we have been solving partial differential equations by using corrected Fourier ...
Nor Hafizah Zainal, Adem Kılıçman
doaj   +1 more source

YIPFα1A expression is regulated by multilayered molecular mechanisms

open access: yesFEBS Open Bio, EarlyView.
YIPFα1A, a five‐pass Golgi protein, is regulated at multiple layers. (1) Rare‐codon enrichment drives translation‐coupled mRNA decay. (2) A proximal 3′‐UTR element stabilizes mRNA. (3) A distal 3′‐UTR element included by alternate poly(A) site usage represses translation, which can be overridden by the proximal 3′‐UTR element.
Tokio Takaji   +2 more
wiley   +1 more source

Fractional equations and diffusive systems: an overview [PDF]

open access: yes, 2013
The aim of this discussion is to give a broad view of the links between fractional differential equations (FDEs) or fractional partial differential equations (FPDEs) and so-called diffusive representations (DR).
Matignon, Denis
core  

Molecular dynamics simulations of positively selected codons in FcγRI reveal novel biochemical binding properties

open access: yesFEBS Open Bio, EarlyView.
Evolutionary analysis across 32 placental mammals identified positive selection at residues H148 and W149 in the immune receptor FcγR1. Ancestral reconstruction combined with molecular dynamics simulations reveals how these mutations may influence receptor structure and dynamics, providing insight into the evolution of antibody recognition and immune ...
David A. Young   +7 more
wiley   +1 more source

Variational iteration method combined with new transform to solve fractional partial differential equations

open access: yesUniversal Journal of Mathematics and Applications, 2018
The aim of this paper is to combined the variational iteration method with Aboodh transform method to solve linear and nonlinear fractional partial differential equations.
Mountassir Hamdi Cherif, Djelloul Ziane
doaj   +1 more source

Acute caffeine treatment protects the developing retina from ischemia‐induced cell death

open access: yesFEBS Open Bio, EarlyView.
Caffeine reduces cell death in the developing retina under ischemia (OGD). This effect does not involve BDNF upregulation or antioxidant pathways (NRF2/VEGF). Neuroprotection occurs mainly through adenosine A2A receptor antagonism, decreasing glutamate release and excitotoxicity, highlighting caffeine's potential as an acute neuroprotective agent in ...
Amanda Alves Nascimento   +6 more
wiley   +1 more source

Space–time fractional stochastic partial differential equations

open access: yesStochastic Processes and their Applications, 2015
25 ...
Mijena, Jebessa B., Nane, Erkan
openaire   +3 more sources

Pharmacological inhibition of the PERK pathway modulates hepatocellular carcinoma growth and immune signaling

open access: yesFEBS Open Bio, EarlyView.
Pharmacological inhibition of PERK in a DEN‐induced mouse model of liver cancer does not reduce tumor burden but alters cellular stress signaling. Despite blocking PERK activity, downstream stress responses, including CHOP expression, remain active, suggesting compensatory mechanisms within the unfolded protein response that may influence tumor ...
Ada Lerma‐Clavero   +5 more
wiley   +1 more source

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