Results 111 to 120 of about 6,741,091 (278)

Evolution‐guided yeast complementation reveals functional differences in human PSPH variants

open access: yesFEBS Open Bio, EarlyView.
Ancient genomes can help guide which human genetic variants are tested experimentally. This study applies that idea to PSPH, a gene involved in serine biosynthesis, and uses high‐throughput yeast complementation to compare variant function. The findings reveal measurable differences among selected alleles and illustrate the value of evolution‐guided ...
Mauricio Campa‐Álvarez   +6 more
wiley   +1 more source

Uniform exponential stability of linear almost periodic systems in Banach spaces

open access: yesElectronic Journal of Differential Equations, 2000
This article is devoted to the study linear non-autonomous dynamical systems possessing the property of uniform exponential stability. We prove that if the Cauchy operator of these systems possesses a certain compactness property, then the uniform ...
David N. Cheban
doaj  

Structural studies and functional engineering of NanX: an anhydro‐sialic acid transporter from Escherichia coli

open access: yesFEBS Open Bio, EarlyView.
Biophysical characterisation shows that NanX, a membrane transport protein from the major facilitator superfamily (MFS), forms both monomers and dimers after purification. AlphaFold modelling and substrate docking provide information on residues likely involved in substrate recognition for NanX and another MFS member, NanT.
Michael C. Newton‐Vesty   +13 more
wiley   +1 more source

Purification and preparation of Marchantia polymorpha Auxin Response Factor 2 for phase separation studies

open access: yesFEBS Open Bio, EarlyView.
We describe detailed protocols for the purification and preparation of Marchantia polymorpha Auxin Response Factor 2 (MpARF2). This protein is fused to an MBP solubility tag and an mNG fluorescent tag and is purified from Escherichia coli. The presented procedures make it possible to study MpARF2 assemblies, which could arise from phase separation ...
Bas Janssen   +5 more
wiley   +1 more source

Weighted pseudo-almost periodic solutions for some neutral partial functional differential equations

open access: yesElectronic Journal of Differential Equations, 2012
In this article we study the existence of weighted pseudo almost periodic solutions of an autonomous neutral functional differential equation with Stepanov-Weighted pseudo almost periodic terms in a Banach space.
Mondher Damak   +2 more
doaj  

Protocol for quantifying miRNA trafficking across the endosomal membrane

open access: yesFEBS Open Bio, EarlyView.
An in vitro protocol measures miRNA uptake into endosomes isolated from mammalian cell extracts, which are free of subcellular contaminants. Performed at 37 °C in the presence of ATP, it ensures the import of single‐stranded miRNA into the endosomal lumen.
Syamantak Ghosh   +2 more
wiley   +1 more source

Weighted pseudo-almost periodic solutions for some neutral partial functional differential equations

open access: yesElectronic Journal of Differential Equations, 2010
In this work, we give sufficient conditions for the existence and uniqueness of a weighted pseudo-almost periodic solutions for some neutral partial functional differential equations.
Khalil Ezzinbi   +2 more
doaj  

Partial differential equations with Fourier series and boundary value problems / NakhleÌ H. Asmar.

open access: yes, 2005
Rev. ed of: Partial differential equations and boundary value problems. 1st ed. Upper Saddle River, NJ : Pearson Prentice Hall, c2000.Includes bibliographical references and index.1 v. (various pgs.)
Asmar, NakhleÌ H. Partial differential equations and boundary value problems. 6715   +1 more
core  

Heterotropic regulation and negative homotropic cooperativity

open access: yesFEBS Open Bio, EarlyView.
We identified a structural module common to some proteins that couple negative cooperativity with heterotropic regulation, two features that rarely coexist. These proteins are ring‐like and present an ordered asymmetry whereby noncontacting subunits are symmetric, and their tertiary structure differs from that of contacting subunits.
Veronica Morea   +5 more
wiley   +1 more source

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