Results 151 to 160 of about 269,773 (341)

Molecular dynamics simulations of positively selected codons in FcγRI reveal novel biochemical binding properties

open access: yesFEBS Open Bio, EarlyView.
Evolutionary analysis across 32 placental mammals identified positive selection at residues H148 and W149 in the immune receptor FcγR1. Ancestral reconstruction combined with molecular dynamics simulations reveals how these mutations may influence receptor structure and dynamics, providing insight into the evolution of antibody recognition and immune ...
David A. Young   +7 more
wiley   +1 more source

Conservation Laws of Discrete Korteweg-de Vries Equation

open access: yesSymmetry, Integrability and Geometry: Methods and Applications, 2005
All three-point and five-point conservation laws for the discrete Korteweg-de Vries equations are found. These conservation laws satisfy a functional equation, which we solve by reducing it to a system of partial differential equations.
Olexandr G. Rasin, Peter E. Hydon
doaj  

Acute caffeine treatment protects the developing retina from ischemia‐induced cell death

open access: yesFEBS Open Bio, EarlyView.
Caffeine reduces cell death in the developing retina under ischemia (OGD). This effect does not involve BDNF upregulation or antioxidant pathways (NRF2/VEGF). Neuroprotection occurs mainly through adenosine A2A receptor antagonism, decreasing glutamate release and excitotoxicity, highlighting caffeine's potential as an acute neuroprotective agent in ...
Amanda Alves Nascimento   +6 more
wiley   +1 more source

Weighted pseudo-almost periodic solutions for some neutral partial functional differential equations

open access: yesElectronic Journal of Differential Equations, 2010
In this work, we give sufficient conditions for the existence and uniqueness of a weighted pseudo-almost periodic solutions for some neutral partial functional differential equations.
Khalil Ezzinbi   +2 more
doaj  

Pharmacological inhibition of the PERK pathway modulates hepatocellular carcinoma growth and immune signaling

open access: yesFEBS Open Bio, EarlyView.
Pharmacological inhibition of PERK in a DEN‐induced mouse model of liver cancer does not reduce tumor burden but alters cellular stress signaling. Despite blocking PERK activity, downstream stress responses, including CHOP expression, remain active, suggesting compensatory mechanisms within the unfolded protein response that may influence tumor ...
Ada Lerma‐Clavero   +5 more
wiley   +1 more source

Weighted pseudo-almost periodic solutions for some neutral partial functional differential equations

open access: yesElectronic Journal of Differential Equations, 2012
In this article we study the existence of weighted pseudo almost periodic solutions of an autonomous neutral functional differential equation with Stepanov-Weighted pseudo almost periodic terms in a Banach space.
Mondher Damak   +2 more
doaj  

Lipopolysaccharide uptake is augmented in lipopolysaccharide‐tolerant mouse macrophage‐like cells via increased CD14 expression

open access: yesFEBS Open Bio, EarlyView.
In normal (nontolerant) cells, CD14 is crucial for both LPS uptake and LPS signaling. In LPS‐tolerant cells, in which LPS‐induced TNF‐α and IFN‐β production is suppressed, there is a dramatic increase in surface CD14 expression. The overexpressed CD14 in LPS‐tolerant cells is responsible for the enhanced LPS uptake without inducing pro‐inflammatory ...
Saeka Nishihara   +3 more
wiley   +1 more source

Weighted pseudo periodic solutions of neutral functional differential equations

open access: yesElectronic Journal of Differential Equations, 2014
In this article, we introduced and explore the properties of two sets of functions: weighted pseudo periodic functions of class r, and weighted Stepanov-like pseudo periodic functions of class r. We show the existence and uniqueness of weighted pseudo
Zhinan Xia
doaj  

On the resolvent of linear nonautonomous partial functional differential equations

open access: yesJournal of Differential Equations, 1985
See the preview in Zbl 0545.34047.
openaire   +2 more sources

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