Results 91 to 100 of about 6,376,169 (271)
Molecular Oncology, EarlyView.Taxanes are widely used chemotherapeutics whose effects on cellular mechanics remain poorly understood. We show that paclitaxel induces rapid cellular contraction by promoting GEF‐H1 dissociation from microtubules and non‐muscle myosin II activation through RhoA/ROCK.
Gloria Asensio‐Juárez +5 more
wiley +1 more source
Molecular Oncology, EarlyView.Isocitrate dehydrogenase 1 (IDH1) mutations are highly recurrent in multiple human cancer types, including cholangiocarcinoma and glioma. IDH1 R132C is the most common IDH1 mutation in cholangiocarcinoma and likely arises from APOBEC3A‐ or APOBEC3B‐mediated deamination.
Kelly E. Butler +3 more
wiley +1 more source
Extrapolation techniques for first order hyperbolic partial differential equations [PDF]
, 1980 A uniform grid of step size h is superimposed on the space variable x in the first order hyperbolic partial differential equation ∂u/∂t + a ∂u/∂x = 0 (a > 0, x > 0, t > 0).
Twizell, E H
core +2 more sources
Molecular Oncology, EarlyView.Incomplete microwave ablation (iMWA) of liver cancer triggers a biphasic progression in residual tumors. At Day 3, the microenvironment is characterized by acute inflammatory responses and extracellular matrix (ECM) remodeling. By Day 14, a profound shift occurs toward oncogenic signal transduction and immunosuppression, marked by macrophage ...
Yu Liu +9 more
wiley +1 more source
Iterative methods for the darboux problem for partial functional differential equations
Journal of Inequalities and Applications, 1999 We consider the Darboux problem for the hyperbolic partial functional differential equations where is a function defined by . If then using the method of functional differential inequalities we prove, under suitable conditions, a theorem on the ...
Człapiński Tomasz
doaj
The system of partial differential equations for the Function
Nuclear Physics, 2019 We present an approach to analyze the scalar integrals of any Feynman diagrams in detail here. This method not only completely recovers some well-known results in the literature, but also produces some new results on the C0 function. The approach can be employed to evaluate the coefficient of arbitrary power of ε in the expansion of a scalar integral ...
Feng, Tai-Fu +3 more
openaire
Molecular Oncology, EarlyView.The kinase SRPK1 directly interacts with the protein TOPBP1 and regulates the pre‐mRNA splicing of WIZ thereby contributing to the activation of the ATR/CHK1 replicative checkpoint in response to replicative stress. This allows cancer cells' genomic stability and survival.
Amani Shreim +17 more
wiley +1 more source
FEBS Open Bio, EarlyView.This protocol paper outlines methods to establish the success of a time‐resolved serial crystallographic experiment, by means of statistical analysis of timepoint data in reciprocal space and models in real space. We show how to amplify the signal from excited states to visualise structural changes in successful experiments.
Jake Hill +4 more
wiley +1 more source
Uniform exponential stability of linear almost periodic systems in Banach spaces
Electronic Journal of Differential Equations, 2000 This article is devoted to the study linear non-autonomous dynamical systems possessing the property of uniform exponential stability. We prove that if the Cauchy operator of these systems possesses a certain compactness property, then the uniform ...
David N. Cheban
doaj
Partial Differential Equations and Generalized Analytic Functions [PDF]
Proceedings of the National Academy of Sciences, 1950 openaire +2 more sources