Effect of cyclosporine on hepatic energy status and on fructose metabolism after portacaval shunt in dog as monitored by phosphorus‐31 nuclear magnetic resonance spectroscopy in vivo [PDF]
, 1991 The effect of cyclosporin A on the hepatic energy status and intracellular pH of the liver and its response to a fructose challenge has been investigated using in vivo phosphorus‐31 nuclear magnetic resonance spectroscopy in dogs.
Atkinson +37 more
core +1 more source
Low‐intervention clinical trials in Spain: Do they progress?
British Journal of Clinical Pharmacology, EarlyView.Abstract Aims Low‐Intervention Clinical Trials (LICTs) are generally pragmatic trials that investigate medicinal products already authorized for use. In 2014, simplified regulatory frameworks were introduced for LICTs with the aim of reducing regulatory burden and operational complexity, to foster non‐commercial clinical trials (NCCTs); the mandatory ...
Claudia Erika Delgado‐Espinoza +4 more
wiley +1 more source
The beneficial effect of α-tocopherol on liver regeneration after partial hepatectomy on rats
The Saudi Journal of Gastroenterology, 1999 Liver, a unique organ, is the only organ which has the ability to regenerate after partial hepatectomy. It can return to normal mass several weeks after 70% partial hepatectomy.
Al Dohayan Abdullah
doaj
Early increases in plasminogen activator activity following partial hepatectomy in humans [PDF]
, 2004 Background Increases in urokinase-like plasminogen activator (uPA) activity are reported to be amongst the earliest events occurring in remnant liver following partial hepatectomy in rats, and have been proposed as a key component of the regenerative ...
Bird, N.C. +3 more
core +2 more sources
PLASMA PROTHROMBIN: EFFECT OF PARTIAL HEPATECTOMY [PDF]
Journal of Experimental Medicine, 1938 Extirpation of a large portion of the liver in rats results in a marked decrease in the plasma prothrombin. The plasma prothrombin level gradually returns to normal during the period required for restoration of the liver to its normal weight. The decrease in prothrombin incident to partial hepatectomy supports the thesis that the liver is concerned in ...
openaire +2 more sources
Paediatric development of radiopharmaceutical imaging agents and radioligand therapeutics
British Journal of Clinical Pharmacology, EarlyView.Abstract This review focuses on the development of radiopharmaceutical imaging agents and radioligand therapeutics for paediatric use. Nuclear medicine plays an important role in the diagnosis and treatment of various childhood conditions, including cancers, infections and brain disorders.
Justin L. Hay +5 more
wiley +1 more source
Further steps of hepatic stimulatory substance purification [PDF]
, 1991 The hepatic stimulatory substance (HSS) extracted from weanling rat livers was purified 381,000-fold using chromatographic techniques including nondissociating polyacrylamide gel electrophoresis (nondenaturing PAGE).
Barone, M +5 more
core +1 more source
Stimulation of Growth by Partial Hepatectomy.
Experimental Biology and Medicine, 1959 SummaryIt has been shown by others that partial hepatectomy in one partner of parabiotic rats induced mitoses in liver of the other, intact parabiont. We found previously that growth of transplanted tumors was enhanced by partial hepatectomy of the host.
K E, PASCHKIS +3 more
openaire +2 more sources
Laparoscopic Partial Hepatectomy of Focal Nodular Hyperplasia
Case Reports in Gastroenterology, 2012 Focal nodular hyperplasia is a benign liver lesion incidentally discovered with increasing frequency because of the proliferation of imaging studies.
Mayu Sakata +9 more
doaj +1 more source
Liver-specific knockout of arginase-1 leads to a profound phenotype similar to inducible whole body arginase-1 deficiency [PDF]
, 2016 Arginase-1 (Arg1) converts arginine to urea and ornithine in the distal step of the urea cycle in liver. We previously generated a tamoxifen-inducible Arg1 deficient mouse model (Arg1-Cre) that disrupts Arg1 expression throughout the whole body and leads
Al-Dirbashi, Osama Y. +5 more
core +1 more source