Results 81 to 90 of about 297,317 (304)
Evolutionarily divergent DUF4465 domains have a common vitamin B12‐binding function
FEBS Open Bio, EarlyView.We show that DUF4465 family proteins, widespread across bacteria from gut microbiomes, hydrothermal vents, and soil, share a common vitamin B12‐binding function. These augmented β‐jellyroll proteins bind vitamin B12 via extended loops. Our findings establish sequence‐diverse DUF4465 proteins as a widespread class of B12‐binding proteins, highlighting ...
Charlea Clarke +4 more
wiley +1 more source
FEBS Open Bio, EarlyView.Bioscience students were asked for their opinions on the value and teaching of skills. 204 responded that teamwork, time management and study skills are necessary to reach University, that scientific writing, research, laboratory and presentation skills are taught effectively during their studies, while other skills are gained inherently through study ...
Janella Borrell, Susan Crennell
wiley +1 more source
Kernel partial least squares for stationary data
J. Mach. Learn. Res., 2017 We consider the kernel partial least squares algorithm for non-parametric regression with stationary dependent data. Probabilistic convergence rates of the kernel partial least squares estimator to the true regression function are established under a source and an effective dimensionality condition.
Singer, Marco +2 more
openaire +5 more sources
FEBS Open Bio, EarlyView.Evolutionary analysis across 32 placental mammals identified positive selection at residues H148 and W149 in the immune receptor FcγR1. Ancestral reconstruction combined with molecular dynamics simulations reveals how these mutations may influence receptor structure and dynamics, providing insight into the evolution of antibody recognition and immune ...
David A. Young +7 more
wiley +1 more source
Guiding AlphaFold to predict how Munc13‐1 opens Syntaxin‐1
FEBS Open Bio, EarlyView.The syntaxin‐1 Habc‐domain (orange), linker (pink) and SNARE motif (yellow) form a closed conformation that binds to Munc18‐1 (violet) and is opened by the Munc13‐1 MUN domain (cyan) to form the SNARE complex that triggers neurotransmitter release.
Madhurima Chattopadhyay +2 more
wiley +1 more source
E-Jurnal Matematika, 2019 Schizophrenia is a psychotic disorder characterized by major disorders in the mind and emotions. People with schizophrenia (ODS) can experience recurrence if they do not receive proper care. The latent variable used in this study was ODS reccurence.
IRA INDRIYANTI +2 more
doaj +1 more source
Tensor Envelope Partial Least-Squares Regression
Technometrics, 2017 Partial least squares (PLS) is a prominent solution for dimension reduction and high-dimensional regressions. Recent prevalence of multidimensional tensor data has led to several tensor versions of the PLS algorithms. However, none offers a population model and interpretation, and statistical properties of the associated parameters remain intractable ...
Xin Zhang 0132, Lexin Li
openaire +1 more source
Partial least square analysis.
, 2014 Results of partial least squares (PLS) model in which porcine gene expression data (Ο) were used for regression analysis with locations in the intestine and the human (□) and murine data (Δ) were projected in the model.
Nicole J. W. de Wit (223526) +12 more
core +1 more source
Molecular characterization of covRS mutations in M1UK Streptococcus pyogenes
FEBS Open Bio, EarlyView.Group A Streptococcus (GAS) acquires covRS mutations driving a hypervirulent bacterial state, frequently associated with invasive disease‐like necrotizing fasciitis. We demonstrate that the newly emerged M1UK GAS lineage can also acquire these mutations.
Jarrad Pritchard +12 more
wiley +1 more source
Pemodelan Ketahanan Pangan Indonesia dengan Menggunakan Partial Least Square Path Modelling (PLS-PM)
, 2012 More priority to food security for every individual to gain access to nutritious food and its absorption by the achievement of a healthy and productive life.
Ningsi, Besse Arna wisuda
core