Results 51 to 60 of about 397,898 (309)

Stability indicating analysis of bisacodyl by partial least squares regression, spectral residual augmented classical least squares and support vector regression chemometric models: A comparative study

Bulletin of Faculty of Pharmacy Cairo University, 2011
Partial least squares regression (PLSR), spectral residual augmented classical least squares (SRACLS) and support vector regression (SVR) are three different chemometric models.
Ibrahim A. Naguib
doaj   +1 more source

Plecstatin inhibits hepatocellular carcinoma tumorigenesis and invasion through cytolinker plectin

Molecular Oncology, EarlyView.
The ruthenium‐based metallodrug plecstatin exerts its anticancer effect in hepatocellular carcinoma (HCC) primarily through selective targeting of plectin. By disrupting plectin‐mediated cytoskeletal organization, plecstatin inhibits anchorage‐dependent growth, cell polarization, and tumor cell dissemination.
Zuzana Outla, Jan Kosla, Magdalena Prechova, Lukas Frick, Patricia Bortel, Yasmin Borutzki, Andrea Bileck, Christopher Gerner, Samuel M. Meier‐Menches, Selma Osmanagic‐Myers, Martin Gregor   +10 more
wiley   +1 more source

Recurrent cancer‐associated ERBB4 mutations are transforming and confer resistance to targeted therapies

Molecular Oncology, EarlyView.
We show that the majority of the 18 analyzed recurrent cancer‐associated ERBB4 mutations are transforming. The most potent mutations are activating, co‐operate with other ERBB receptors, and are sensitive to pan‐ERBB inhibitors. Activating ERBB4 mutations also promote therapy resistance in EGFR‐mutant lung cancer.
Veera K. Ojala, Sini Ahonen, Sara Peltola, Aura Tuohisto‐Kokko, Olaya Esparta, Peppi Suominen, Anne Jokilammi, Iman Farahani, Deepankar Chakroborty, Nikol Dibus, Steffen Boettcher, Tomi T. Airenne, Mark S. Johnson, Lisa D. Eli, Klaus Elenius, Kari J. Kurppa   +15 more
wiley   +1 more source

Improving the Performance of Robust Partial Least Squares Regression Using an Iterative Approach

مجلة الغري للعلوم الاقتصادية والادارية
The robust partial least squares regression method provides a solution to noise and outliers in the estimated models by maximizing the explanation ratios of the independent and dependent variables (determination coefficient). Three proposed methods were
Mahammad Mahmoud Bazid Bazid, Taha Hussein Ali Ali   +1 more
doaj   +1 more source

Peroxidasin enables melanoma immune escape by inhibiting natural killer cell cytotoxicity

Molecular Oncology, EarlyView.
Peroxidasin (PXDN) is secreted by melanoma cells and binds the NK cell receptor NKG2D, thereby suppressing NK cell activation and cytotoxicity. PXDN depletion restores NKG2D signaling and enables effective NK cell–mediated melanoma killing. These findings identify PXDN as a previously unrecognized immune evasion factor and a potential target to improve
Hsu‐Min Sung, David Bickel, Lena C. M. Krause, Daria Ezeriņa, Christian Ickes, Julian Wojtachnia, Christine S. Gibhardt, Magdalena Shumanska, Khadija Wahni, Andrea Paluschkiwitz, Julia Malo Pueyo, Ekaterina Baranova, Wim Vranken, Hedwig Stanisz, Ioana Stejerean‐Todoran, Michael P. Schön, Joris Messens, Ivan Bogeski   +17 more
wiley   +1 more source

Optimization of wood flour acetylation by factorial design and partial least squares regression

Química Nova, 2012
Acetylation was performed to reduce the polarity of wood and increase its compatibility with polymer matrices for the production of composites. These reactions were performed first as a function of acetic acid and anhydride concentration in a mixture ...
Lisandra M. K. Nadal, Daniele C. Cararo, Luís A. Pinheiro, Rosilene A. Prestes   +3 more
doaj   +1 more source

A comparison Between Principal Component Regression and Partial Least Squares Regression Methods with application in The Kirkuk Cement

Tikrit Journal of Pure Science, 2023
Appear in Many Application Areas for Regression Analysis and Presence the case of More Than One Variable Dependent Affected by A variety of  Explanatory Variable and at The Same Time The Number of Observation is Relatively Small Compared to The Number ...
Thafer Ramathan Muttar AL-Badrany, Takwa Abdulsalam Taha AL-Mola   +1 more
doaj   +1 more source

Mycobacterial cell division arrest and smooth‐to‐rough envelope transition using CRISPRi‐mediated genetic repression systems

FEBS Open Bio, EarlyView.
CRISPRI‐mediated gene silencing and phenotypic exploration in nontuberculous mycobacteria. In this Research Protocol, we describe approaches to control, monitor, and quantitatively assess CRISPRI‐mediated gene silencing in M. smegmatis and M. abscessus model organisms.
Vanessa Point, Wafaa Achache, Janïs Laudouze, Eliana Sepulveda Ramos, Mickaël Maziero, Céline Crauste, Stéphane Canaan, Pierre Santucci   +7 more
wiley   +1 more source

Partial Least Squares Regression on Symmetric Positive-Definite Matrices

Revista Colombiana de Estadística, 2013
Recientemente ha habido un aumento en el interés de analizar diferentes tipos de datos variedad-valuados, dentro de los cuáles aparecen los datos de matrices simétricas definidas positivas.
RAÚL ALBERTO PÉREZ, GRACIELA GONZÁLEZ-FARIAS   +1 more
doaj  

Significance Regression: A Statistical Approach to Biased Linear Regression and Partial Least Squares [PDF]

, 1993
This paper first examines the properties of biased regressors that proceed by restricting the search for the optimal regressor to a subspace. These properties suggest features such biased regression methods should incorporate.
Hjalmarsson, Hakan, Holcomb, Tyler R., Morari, Manfred   +2 more
core   +1 more source