Results 61 to 70 of about 458,963 (267)

Wheezing Sound Separation Based on Informed Inter-Segment Non-Negative Matrix Partial Co-Factorization

Sensors, 2020
Wheezing reveals important cues that can be useful in alerting about respiratory disorders, such as Chronic Obstructive Pulmonary Disease. Early detection of wheezing through auscultation will allow the physician to be aware of the existence of the ...
Juan De La Torre Cruz, Francisco Jesús Cañadas Quesada, Nicolás Ruiz Reyes, Pedro Vera Candeas, Julio José Carabias Orti   +4 more
doaj   +1 more source

Existence of solutions for 4p-order PDES with Neumann boundary conditions

Moroccan Journal of Pure and Applied Analysis, 2023
In this work, we study the existence of at least one non decreasing sequence of nonnegative eigenvalues for the problem: {Δ2pu=λm(x)u   in   Ω,∂u∂v=∂(Δu)∂v=…=∂(Δ2p-1u)∂v=0   on   ∂Ω.\left\{ {\matrix{ {{\Delta ^{2p}}u = \lambda m\left( x \right)u ...
Moradi N., Moradi F., Habib S. El, Addam M.   +3 more
doaj   +1 more source

Recurrent cancer‐associated ERBB4 mutations are transforming and confer resistance to targeted therapies

Molecular Oncology, EarlyView.
We show that the majority of the 18 analyzed recurrent cancer‐associated ERBB4 mutations are transforming. The most potent mutations are activating, co‐operate with other ERBB receptors, and are sensitive to pan‐ERBB inhibitors. Activating ERBB4 mutations also promote therapy resistance in EGFR‐mutant lung cancer.
Veera K. Ojala, Sini Ahonen, Sara Peltola, Aura Tuohisto‐Kokko, Olaya Esparta, Peppi Suominen, Anne Jokilammi, Iman Farahani, Deepankar Chakroborty, Nikol Dibus, Steffen Boettcher, Tomi T. Airenne, Mark S. Johnson, Lisa D. Eli, Klaus Elenius, Kari J. Kurppa   +15 more
wiley   +1 more source

Peroxidasin enables melanoma immune escape by inhibiting natural killer cell cytotoxicity

Molecular Oncology, EarlyView.
Peroxidasin (PXDN) is secreted by melanoma cells and binds the NK cell receptor NKG2D, thereby suppressing NK cell activation and cytotoxicity. PXDN depletion restores NKG2D signaling and enables effective NK cell–mediated melanoma killing. These findings identify PXDN as a previously unrecognized immune evasion factor and a potential target to improve
Hsu‐Min Sung, David Bickel, Lena C. M. Krause, Daria Ezeriņa, Christian Ickes, Julian Wojtachnia, Christine S. Gibhardt, Magdalena Shumanska, Khadija Wahni, Andrea Paluschkiwitz, Julia Malo Pueyo, Ekaterina Baranova, Wim Vranken, Hedwig Stanisz, Ioana Stejerean‐Todoran, Michael P. Schön, Joris Messens, Ivan Bogeski   +17 more
wiley   +1 more source

Design of Partial Mueller-Matrix Polarimeters for Application-Specific Sensors

Sensors
At a particular frequency, most materials and objects of interest exhibit a polarization signature, or Mueller matrix, of limited dimensionality, with many matrix elements either negligibly small or redundant due to symmetry.
Brian G. Hoover, Martha Y. Takane
doaj   +1 more source

Crucial parameters for precise copy number variation detection in formalin‐fixed paraffin‐embedded solid cancer samples

Molecular Oncology, EarlyView.
This study shows that copy number variations (CNVs) can be reliably detected in formalin‐fixed paraffin‐embedded (FFPE) solid cancer samples using ultra‐low‐pass whole‐genome sequencing, provided that key (pre)‐analytical parameters are optimized.
Hanne Goris, Vasiliki Siozopoulou, Léon C van Kempen, Anne Sieben, Ella Roelant, Stig Hellemans, Elyne Backx, Laure Sorber, Koen De Winne, Senada Koljenović, Karen Zwaenepoel   +10 more
wiley   +1 more source

Some results on the partial orderings of block matrices

Journal of Inequalities and Applications, 2011
Some results relating to the block matrix partial orderings and the submatrix partial orderings are given. Special attention is paid to the star ordering of a sum of two matrices and the minus ordering of matrix product. Several equivalent conditions for
Liu Xifu, Yang Hu
doaj  

Group-Theoretic Partial Matrix Multiplication

, 2009
A generalization of recent group-theoretic matrix multiplication algorithms to an analogue of the theory of partial matrix multiplication is presented. We demonstrate that the added flexibility of this approach can in some cases improve upper bounds on the exponent of matrix multiplication yielded by group-theoretic full matrix multiplication.
Bowen, Richard Strong, Chen, Bo, Orem, Hendrik, van Schaardenburg, Martijn   +3 more
openaire   +2 more sources

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

Molecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

RaMBat: Accurate identification of medulloblastoma subtypes from diverse data sources with severe batch effects

Molecular Oncology, EarlyView.
To integrate multiple transcriptomics data with severe batch effects for identifying MB subtypes, we developed a novel and accurate computational method named RaMBat, which leveraged subtype‐specific gene expression ranking information instead of absolute gene expression levels to address batch effects of diverse data sources.
Mengtao Sun, Jieqiong Wang, Shibiao Wan
wiley   +1 more source