Results 31 to 40 of about 27,193 (265)
Reconstructing enzyme evolution by protein engineering
FEBS Letters, EarlyView.Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler +2 more
wiley +1 more source
Geophysical Research LettersRecent studies have challenged the classical view of magma chambers as ephemeral, melt‐rich bodies confined to shallow depths beneath arc volcanoes at subduction zones.
Qili Andy Dai +4 more
doaj +1 more source
MethodsX, 2020 The melt content is significant characteristic for the low velocity layer, so it is very necessary to set up the quantitative relationship between the low velocity anomaly and the melt fraction.
Maining Ma +3 more
doaj +1 more source
Peripheral lysosomes recruit PLEKHG3 to focal adhesions and restrain protrusion dynamics
FEBS Letters, EarlyView.Proximity‐dependent labeling at the LAMTOR complex revealed the Rho GEF PLEKHG3 as a lysosome‐proximal protein directing the study toward the influence of lysosome positioning on actin dynamics and cell motility. We show that PLEKHG3 colocalizes with lysosomes at focal adhesion sites and observe that forced peripheral dispersion of lysosomes hinders ...
Rainer Ettelt +8 more
wiley +1 more source
Partial Melting of Lower Oceanic Crust Gabbro: Constraints From Poikilitic Clinopyroxene Primocrysts
Frontiers in Earth Science, 2018 Successive magma batches underplate, ascend, stall and erupt along spreading ridges, building the oceanic crust. It is therefore important to understand the processes and conditions under which magma differentiates at mid ocean ridges.
Julien Leuthold +6 more
doaj +1 more source
Thermal conditions during deformation of partially molten crust from TitaniQ geothermometry: rheological implications for the anatectic domain of the Araçuaí belt, eastern Brazil [PDF]
Solid Earth, 2014 During the Neoproterozoic orogeny, the middle crust of the Araçuaí belt underwent widespread partial melting. At the regional scale, this anatectic domain is characterized by a progressive rotation of the flow direction from south to north, suggesting a ...
G. C. G. Cavalcante +5 more
doaj +1 more source
Golgi enzymes are retrieved from the plasma membrane to the trans‐Golgi network
FEBS Letters, EarlyView.Golgi enzymes are traditionally considered resident proteins retained within the Golgi apparatus. Here, we demonstrate that a subset transiently reaches the cell surface and is subsequently retrieved to the trans‐Golgi network via retrograde transport. Using a nanobody‐based toolkit, we uncover a dynamic trafficking cycle of several Golgi enzymes.
Dominik P. Buser, Tina Junne
wiley +1 more source
Permeability Models for Magma Flow through the Earth's Mantle: A Lie Group Analysis
Journal of Applied Mathematics, 2013 The migration of melt through the mantle of the Earth is governed by a third-order nonlinear partial differential equation for the voidage or volume fraction of melt.
N. Mindu, D. P. Mason
doaj +1 more source
Results in Engineering, 2023 This paper presents the effects of cross fluid model associated with entropy generation and melt process. The Cross-fluid viscosity model based on the infinite shear rate effect is taken with attaching Riga plate.
Adil Darvesh +6 more
doaj +1 more source
Molecular Oncology, EarlyView.In this explorative study, the abundance of circular RNA molecules in bone marrow stem cells was found to be elevated in patients with high‐risk myelodysplastic neoplasms, and to be associated with an increased risk of progression to acute myeloid leukemia.
Eileen Wedge +17 more
wiley +1 more source