Results 61 to 70 of about 27,193 (265)

Suppression of lung adenocarcinoma migration through organelle alkalization by human lactoferrin – albumin fusion

open access: yesFEBS Open Bio, EarlyView.
This paper reveals how human lactoferrin–albumin fusion (hLF‐HSA) potently suppresses lung adenocarcinoma cell migration. hLF‐HSA upregulates NHE7, leading to Golgi alkalization, disruption of the Golgi secretome, downregulation of MMP1, and reversal of EMT. These findings suggest a novel Golgi‐targeting strategy to suppress cancer cell migration.
Hana Nopia   +3 more
wiley   +1 more source

YIPFα1A expression is regulated by multilayered molecular mechanisms

open access: yesFEBS Open Bio, EarlyView.
YIPFα1A, a five‐pass Golgi protein, is regulated at multiple layers. (1) Rare‐codon enrichment drives translation‐coupled mRNA decay. (2) A proximal 3′‐UTR element stabilizes mRNA. (3) A distal 3′‐UTR element included by alternate poly(A) site usage represses translation, which can be overridden by the proximal 3′‐UTR element.
Tokio Takaji   +2 more
wiley   +1 more source

New observations of Tin Mineralization Potential Vis-à-Vis Ore Petrographic, Alteration and Geochemistry in the Southeastern part of Bastar Craton, Central India

open access: yesJGEET: Journal of Geoscience, Engineering, Environment and Technology, 2019
The Tin mineralizations occur around the Katekalyan area, hosted in the acid magmatic rocks. The evolution differentiating granitic magma shows residual melt enrichment where end products intruded as pegmatites into the rocks.
Abhimanyu Singh, Vinod K. Singh
doaj   +1 more source

Melt redistribution during the bending of a porous, partially melted layer

open access: yesGeophysical Research Letters, 2003
A numerical, poro‐viscoelastic finite element flow model has been developed to simulate the redistribution of melt during the folding of a horizontal layer. Important mechanical properties governing the overall rheology of the buckling layer, including porosity, matrix viscosity, melt pressure and changes in deviatoric stress are tracked simultaneously
A. G. Simakin, N. Petford
openaire   +1 more source

Acute caffeine treatment protects the developing retina from ischemia‐induced cell death

open access: yesFEBS Open Bio, EarlyView.
Caffeine reduces cell death in the developing retina under ischemia (OGD). This effect does not involve BDNF upregulation or antioxidant pathways (NRF2/VEGF). Neuroprotection occurs mainly through adenosine A2A receptor antagonism, decreasing glutamate release and excitotoxicity, highlighting caffeine's potential as an acute neuroprotective agent in ...
Amanda Alves Nascimento   +6 more
wiley   +1 more source

A yeast model of 5‐oxoproline accumulation reveals a general toleration to 5‐oxoproline

open access: yesFEBS Open Bio, EarlyView.
Using a yeast model, we show that even high accumulation of 5‐oxoproline causes only mild cellular stress and does not trigger oxidative stress. Instead, cells adapt by activating efflux pumps and diverse protective pathways, suggesting that previously proposed harmful effects of 5‐oxoproline may arise from indirect metabolic imbalances rather than the
Pratiksha Dubey   +4 more
wiley   +1 more source

"Early partial melting" in annealed natural cordierites

open access: yesEuropean Journal of Mineralogy, 2002
Natural cordierite crystals with a range of Mg:Fe ratios have been annealed at a range of temperatures between 1200 and 1430°C (under controlled f o2 ), after previously being annealed at 900 °C to drive off any volatiles contained within their channels. Complex microstructures were observed in these samples by transmission electron microscopy.
Capitani, G   +3 more
openaire   +1 more source

Hyperactive ice‐binding proteins stabilize cell membranes and improve resistance to dehydration stress in Caenorhabditis elegans

open access: yesFEBS Open Bio, EarlyView.
TisIBP8, a fungal‐derived hyperactive ice‐binding protein, helps Caenorhabditis elegans survive dehydration. It localizes near cell membranes, reduces cell damage, and helps maintain membrane structure during drying. These results suggest that ice‐binding proteins can protect cells from dehydration stress as well as freezing stress.
Daiki Shimose   +9 more
wiley   +1 more source

Effect of annealing of ZnSe:Cr crystals in Bi(Zn) melt on the intensity of radiation bands of Cr ions

open access: yesMoldavian Journal of the Physical Sciences, 2010
The photoluminescence in visible and near-IR spectral range of ZnSe:Cr as-grown and annealed in Bi(Zn) melt crystals was investigated at room temperature.
Culiuc, Leonid   +3 more
doaj  

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