Results 61 to 70 of about 76,426 (269)

YIPFα1A expression is regulated by multilayered molecular mechanisms

FEBS Open Bio, EarlyView.
YIPFα1A, a five‐pass Golgi protein, is regulated at multiple layers. (1) Rare‐codon enrichment drives translation‐coupled mRNA decay. (2) A proximal 3′‐UTR element stabilizes mRNA. (3) A distal 3′‐UTR element included by alternate poly(A) site usage represses translation, which can be overridden by the proximal 3′‐UTR element.
Tokio Takaji, Yurika Nakanishi, Nobuhiro Nakamura   +2 more
wiley   +1 more source

Melt redistribution during the bending of a porous, partially melted layer

Geophysical Research Letters, 2003
A numerical, poro‐viscoelastic finite element flow model has been developed to simulate the redistribution of melt during the folding of a horizontal layer. Important mechanical properties governing the overall rheology of the buckling layer, including porosity, matrix viscosity, melt pressure and changes in deviatoric stress are tracked simultaneously
A. G. Simakin, N. Petford
openaire   +1 more source

Acute caffeine treatment protects the developing retina from ischemia‐induced cell death

FEBS Open Bio, EarlyView.
Caffeine reduces cell death in the developing retina under ischemia (OGD). This effect does not involve BDNF upregulation or antioxidant pathways (NRF2/VEGF). Neuroprotection occurs mainly through adenosine A2A receptor antagonism, decreasing glutamate release and excitotoxicity, highlighting caffeine's potential as an acute neuroprotective agent in ...
Amanda Alves Nascimento, Danniel Pereira‐Figueiredo, Gabriella Grossi de Lima Dias, Gabriel Ferreira dos Santos, Mariana Rodrigues Pereira, Rafael Brito, Karin C Calaza   +6 more
wiley   +1 more source

A yeast model of 5‐oxoproline accumulation reveals a general toleration to 5‐oxoproline

FEBS Open Bio, EarlyView.
Using a yeast model, we show that even high accumulation of 5‐oxoproline causes only mild cellular stress and does not trigger oxidative stress. Instead, cells adapt by activating efflux pumps and diverse protective pathways, suggesting that previously proposed harmful effects of 5‐oxoproline may arise from indirect metabolic imbalances rather than the
Pratiksha Dubey, Vaishnavi Sanjayan, Praveen Singh, Shantanu Sengupta, Anand Kumar Bachhawat   +4 more
wiley   +1 more source

Archean continental crust formed by magma hybridization and voluminous partial melting. [PDF]

Sci Rep, 2021
Hernández-Montenegro JD, Palin RM, Zuluaga CA, Hernández-Uribe D.   +3 more
europepmc   +1 more source

"Early partial melting" in annealed natural cordierites

European Journal of Mineralogy, 2002
Natural cordierite crystals with a range of Mg:Fe ratios have been annealed at a range of temperatures between 1200 and 1430°C (under controlled f o2 ), after previously being annealed at 900 °C to drive off any volatiles contained within their channels. Complex microstructures were observed in these samples by transmission electron microscopy.
Capitani, G, Doukhan, J, Malchereck, T, Carpenter, M.   +3 more
openaire   +1 more source

Hyperactive ice‐binding proteins stabilize cell membranes and improve resistance to dehydration stress in Caenorhabditis elegans

FEBS Open Bio, EarlyView.
TisIBP8, a fungal‐derived hyperactive ice‐binding protein, helps Caenorhabditis elegans survive dehydration. It localizes near cell membranes, reduces cell damage, and helps maintain membrane structure during drying. These results suggest that ice‐binding proteins can protect cells from dehydration stress as well as freezing stress.
Daiki Shimose, Kotaro Ozaki, Ryohei Kuriyama, Yuka Ikemoto, Kazuhiro Mio, Yuji C. Sasaki, Tatsuya Arai, Sakae Tsuda, Yoichi Shinkai, Masahiro Kuramochi   +9 more
wiley   +1 more source

Molecular characterization of covRS mutations in M1UK Streptococcus pyogenes

FEBS Open Bio, EarlyView.
Group A Streptococcus (GAS) acquires covRS mutations driving a hypervirulent bacterial state, frequently associated with invasive disease‐like necrotizing fasciitis. We demonstrate that the newly emerged M1UK GAS lineage can also acquire these mutations.
Jarrad Pritchard, Emma‐Jayne Proctor, Jiawa Wang, Nikolas P. Johnston, Andrew Hayes, Georgia McCorkell, Haibo Yu, Jai Tree, Mark R. Davies, Mark J. Walker, Ronald Sluyter, Stephan Brouwer, Martina L. Sanderson‐Smith   +12 more
wiley   +1 more source

Petrology of Oligocene Lalehzar igneous rocks in the southeast of Saveh-Naein-Jiroft magmatic belt

Journal of Economic Geology
Lalehzar igneous rocks are located in the southeast of Iran, the SE of Saveh-Naein-Jiroft magmatic belt. In this study, zircon U-Pb dating, and whole-rock geochemistry and Sr-Nd isotopic analyzes were performed on granitoid rocks (granite and ...
Fatemeh Sepidbar, Bahareh Borouzi Niyat
doaj   +1 more source

Partial Melting of Lower Oceanic Crust Gabbro: Constraints From Poikilitic Clinopyroxene Primocrysts

Frontiers in Earth Science, 2018
Successive magma batches underplate, ascend, stall and erupt along spreading ridges, building the oceanic crust. It is therefore important to understand the processes and conditions under which magma differentiates at mid ocean ridges.
Julien Leuthold, C. Johan Lissenberg, Brian O'Driscoll, Ozge Karakas, Trevor Falloon, Dina N. Klimentyeva, Peter Ulmer   +6 more
doaj   +1 more source