Results 131 to 140 of about 1,115,339 (315)

Decreased cold‐sensing function of the transient receptor potential channel TRPM8 from tailed amphibians

open access: yesFEBS Open Bio, EarlyView.
Despite frogs avoiding low temperatures, examination of four salamander species revealed that none avoided cold and all possessed cold tolerance. Functional analysis of TRPM8, a cold sensor, showed that all salamander TRPM8s had lost their cold sensitivity.
Tadahiro Sawao   +3 more
wiley   +1 more source

Evolutionarily divergent DUF4465 domains have a common vitamin B12‐binding function

open access: yesFEBS Open Bio, EarlyView.
We show that DUF4465 family proteins, widespread across bacteria from gut microbiomes, hydrothermal vents, and soil, share a common vitamin B12‐binding function. These augmented β‐jellyroll proteins bind vitamin B12 via extended loops. Our findings establish sequence‐diverse DUF4465 proteins as a widespread class of B12‐binding proteins, highlighting ...
Charlea Clarke   +4 more
wiley   +1 more source

Partial-Order Support-Link Scheduling

open access: yes, 2011
Partial-order schedules are valued because they are flexible, and therefore more robust to unexpected delays. Previous work has indicated that constructing partial-order schedules by a two-stage method, in which a fixed-time schedule is first found and a
Haslum, Patrik, Banerjee, Debdeep
core   +1 more source

Systemic dysregulation of apolipoproteins in amyotrophic lateral sclerosis serum

open access: yesFEBS Open Bio, EarlyView.
Amyotrophic lateral sclerosis (ALS) is a fatal disease that damages motor neurons. This study found that people with ALS show significant changes in blood fats and the proteins that carry them. Several apolipoproteins were higher, lipid balances were altered, and normal protein–lipid relationships were disrupted.
Finula I. Isik   +6 more
wiley   +1 more source

The skills required for transition to university and study in biological sciences: A student perspective

open access: yesFEBS Open Bio, EarlyView.
Bioscience students were asked for their opinions on the value and teaching of skills. 204 responded that teamwork, time management and study skills are necessary to reach University, that scientific writing, research, laboratory and presentation skills are taught effectively during their studies, while other skills are gained inherently through study ...
Janella Borrell, Susan Crennell
wiley   +1 more source

Maximal partial Latin cubes

open access: yes, 2015
We prove that each maximal partial Latin cube must have more than 29.289% of its cells filled and show by construction that this is a nearly tight bound.
Britz, Thomas   +2 more
core  

Partial Symbol Ordering Distance

open access: yes, 2009
Nowadays sequences of symbols are becoming more important, as they are the standard format for representing information in a large variety of domains such as ontologies, sequential patterns or non numerical attributes in databases. Therefore, the development of new distances for this kind of data is a crucial need.
Herranz Sotoca, Javier   +1 more
openaire   +2 more sources

Why human connection is the true metric of research success

open access: yesFEBS Open Bio, EarlyView.
Human‐centred mentorship can be shaped by mentor attributes, actions, intrinsic drive and career ambition. Drawing on reflections across Singapore and France, as well as workshop insights from FEBS‐IUBMB ENABLE 2024, this article shows that human‐centred mentorship creates the conditions for sustainable growth, well‐being and retention in research ...
Timothy Lin Yun Tan   +3 more
wiley   +1 more source

Implicit methods for the simple wave equation

open access: yes, 1984
A family of finite difference methods is developed for the numerical solution of the simple wave equation. Local truncation errors are cal- culated for each member of the family and each is analyzed for stability.
Tirmizi, S I A, Twizell, E H
core  

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