Results 71 to 80 of about 69,240 (308)

Some examples of universal and generic partial orders

open access: yes, 2010
We survey structures endowed with natural partial orderings and prove their universality. These partial orders include partial orders on sets of words, partial orders formed by geometric objects, grammars, polynomials and homomorphism order for various combinatorial objects.
Jan Hubicka, Jaroslav Nesetril
openaire   +2 more sources

Modulation of Homer1 EVH1 domain internal dynamics by putative autism‐associated mutations

open access: yesFEBS Letters, EarlyView.
The putative autism‐associated M65I and S97L variants of the EVH1 domain of the postsynaptic scaffold protein Homer1 do not exhibit substantial changes in their overall structure or partner binding. Both of them, but especially the M65I variant, show altered internal dynamics relative to the wild‐type domain on the μs‐ms timescale, indicated by the ...
Fanni Farkas   +6 more
wiley   +1 more source

TRAIL‐PEG‐Apt‐PLGA nanosystem as an aptamer‐targeted drug delivery system potential for triple‐negative breast cancer therapy using in vivo mouse model

open access: yesMolecular Oncology, EarlyView.
Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat   +8 more
wiley   +1 more source

Analytic Fuzzy Formulation of a Time-Fractional Fornberg–Whitham Model with Power and Mittag–Leffler Kernels

open access: yesFractal and Fractional, 2021
This manuscript assesses a semi-analytical method in connection with a new hybrid fuzzy integral transform and the Adomian decomposition method via the notion of fuzziness known as the Elzaki Adomian decomposition method (briefly, EADM). Moreover, we use
Saima Rashid   +5 more
doaj   +1 more source

Modal and temporal operators on partial orders [PDF]

open access: yes, 2006
We generalize the operators of classical linear time temporal logic to partial orders, such as the ones used in domain theory. This relates denotaional semantics and temporal logic. We put this into the general perspective of modal logic.
Möller, Bernhard (Prof. Dr.)
core  

Fourth order partial differential equations on general geometries [PDF]

open access: yesJournal of Computational Physics, 2006
zbMATH Open Web Interface contents unavailable due to conflicting licenses.
John B. Greer   +2 more
openaire   +1 more source

Circular RNA expression landscapes in myelodysplastic neoplasms: Associations with mutational signatures and disease progression

open access: yesMolecular Oncology, EarlyView.
In this explorative study, the abundance of circular RNA molecules in bone marrow stem cells was found to be elevated in patients with high‐risk myelodysplastic neoplasms, and to be associated with an increased risk of progression to acute myeloid leukemia.
Eileen Wedge   +17 more
wiley   +1 more source

Inter-American Human Rights System and Social Change in Latin America

open access: yesLaws
The role of human rights is increasingly subject to scrutiny and debate. However, historically, human rights functioned as powerful tools for social change. In this context, this paper explores the origin, evolution and impact of the Inter-American Human
Martha Gutiérrez
doaj   +1 more source

Somatic mutational landscape in von Hippel–Lindau familial hemangioblastoma

open access: yesMolecular Oncology, EarlyView.
The causes of central nervous system (CNS) hemangioblastoma in Von Hippel–Lindau (vHL) disease are unclear. We used Whole Exome Sequencing (WES) on familial hemangioblastoma to investigate events that underlie tumor development. Our findings suggest that VHL loss creates a permissive environment for tumor formation, while additional alterations ...
Maja Dembic   +5 more
wiley   +1 more source

,,Cura animarum" of the Preachers Order in the Background of the Medieval Monkhoods Soul Salvation Development

open access: yesLietuvos Istorijos Studijos, 2006
On the 21st of January 1217, St. Dominic Guzman and his order were given the bulla "Gratiarum omnium" from the Pope, Honorius III (1216-1227), which approved their idea of preaching and spreading the Gospel; thus they became independent from the bishops
Slawomir Zonenberg
doaj   +3 more sources

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