Results 81 to 90 of about 12,086,834 (291)

Shadow Cones: A Generalized Framework for Partial Order Embeddings

, 2023
ICLR ...
Tao Yu, Toni J. B. Liu, Albert Tseng, Christopher De Sa   +3 more
openaire   +3 more sources

Translating whole‐genome doubling into precision medicine in cancer

Molecular Oncology, EarlyView.
Whole‐genome doubling creates a WGD‐positive tumor state characterized by persistent chromosomal instability, karyotypic diversification, and cellular stress. These same biological pressures drive aggressive tumor evolution while exposing therapeutic vulnerabilities, providing a rationale for WGD‐informed precision medicine. Whole‐genome doubling (WGD)
Sejung Lee, Junghyeok Lim, Jinhyuk Bhin
wiley   +1 more source

The Various Definitions of Multiple Differentiability of a Function f: ℝⁿ→ ℝ

Mathematics, 2020
Since the 17-th century the concepts of differentiability and multiple differentiability have become fundamental to mathematical analysis. By now we have the generally accepted definition of what a multiply differentiable function f:Rn→R is (in this ...
Alexander Kuleshov
doaj   +1 more source

Targeting transcription factors associated with hemoglobinopathies: Lessons from successful interventions and implications for cancer

Molecular Oncology, EarlyView.
This review summarizes the transcription factors, repressive chromatin‐modifying complexes, and epigenetic mechanisms that control fetal hemoglobin repression. Notably, many regulators of γ‐globin silencing also function in transcriptional and epigenetic networks that drive cancer, highlighting opportunities to translate advances in hemoglobinopathy ...
Meigen Yu, Puspa Das, Xing Zhang, Xiaodong Cheng   +3 more
wiley   +1 more source

Intrapatient tumour heterogeneity and clonal evolution in an autopsy study of metastatic salivary gland cancer

Molecular Oncology, EarlyView.
Tumour heterogeneity and clonal evolution of metastatic salivary gland cancer were evaluated in two patients with adenoid carcinoma and one patient with myoepithelial carcinoma. Radiology‐guided autopsy enabled multi‐region sampling (total samples n = 149), followed by whole‐genome sequencing and phylogenetic reconstruction (17 tumour samples, 4–7 per ...
Gerben Lassche, Niels J. van Ruitenbeek, Charlotte Adang, Luke O'Gorman, Pui Yuen Lee, Willemijn M. Klein, Adriana C. H. van Engen‐van Grunsven, Jack A. Schalken, Sander Bervoets, Gerald W. Verhaegh, Carla M. L. van Herpen   +10 more
wiley   +1 more source

Other title: Online collection of General orders, number two and number six issued by Kansas Adjutant General Milton R. McLean in 1947 Other title: General orders no. 2, Kansas State Guard is changed from its present designation as the First Infantry Regiment to the First Infantry Group Other title: General orders no. 6, announcing the appointment of Albert S. Bigelow as Kansas Assistant Adjutant General

, 1947
Title supplied by cataloger. General Orders no. 2 was released January 1, 1947. General Orders no.
McLean, Milton R., 1874-1951.
core   +1 more source

Design and Control of Fractional-Order Systems Based on Fractal Operators

Fractal and Fractional
In recent years, we have abstracted physical fractal space from biological structures and movements within living organisms, revealing the profound intrinsic connections between fractional order time and fractional-dimensional space, and providing ...
Zhimo Jian, Chaoqian Luo, Yajun Yin
doaj   +1 more source

Novel Dynamic Partial Reconfiguration Implementation of K-Means Clustering on FPGAs: Comparative Results with GPPs and GPUs

International Journal of Reconfigurable Computing, 2012
K-means clustering has been widely used in processing large datasets in many fields of studies. Advancement in many data collection techniques has been generating enormous amounts of data, leaving scientists with the challenging task of processing them ...
Hanaa M. Hussain, Khaled Benkrid, Ali Ebrahim, Ahmet T. Erdogan, Huseyin Seker   +4 more
doaj   +1 more source

An efficient construction of polar codes based on the general partial order

EURASIP Journal on Wireless Communications and Networking, 2019
Traditionally, the construction of polar codes requires intense computations to sort all bit channels. In previous works, two types of partial orders (POs) of polar codes were proposed to decrease the computations in the construction process.
Wei Wang, Liping Li, Kai Niu
doaj   +1 more source