Results 61 to 70 of about 2,250,867 (343)

Microbial exopolysaccharide production by polyextremophiles in the adaptation to multiple extremes

FEBS Letters, EarlyView.
Polyextremophiles are microorganisms that endure multiple extreme conditions by various adaptation strategies that also include the production of exopolysaccharides (EPSs). This review provides an integrated perspective on EPS biosynthesis, function, and regulation in these organisms, emphasizing their critical role in survival and highlighting their ...
Tracey M Gloster, Ebru Toksoy Öner
wiley   +1 more source

Exact Solutions of the 3D Fractional Helmholtz Equation by Fractional Differential Transform Method

Journal of Function Spaces, 2022
In this work, we applied the fractional reduced differential transform method (FRDTM) to find the exact solutions of the three-dimensional fractional Helmholtz equation (FHE) and compared our outcomes with the tenth-order approximate solutions for ...
Saleh Alshammari, Salah Abuasad
doaj   +1 more source

An Efficient Technique of Fractional-Order Physical Models Involving ρ-Laplace Transform

Mathematics, 2022
In this article, the ρ-Laplace transform is paired with a new iterative method to create a new hybrid methodology known as the new iterative transform method (NITM).
Nehad Ali Shah, Ioannis Dassios, Essam R. El-Zahar, Jae Dong Chung   +3 more
doaj   +1 more source

Structural dynamics of the plant hormone receptor ETR1 in a native‐like membrane environment

FEBS Letters, EarlyView.
The present study unveils the structural and signaling dynamics of ETR1, a key plant ethylene receptor. Using an optimized nanodisc system and solution NMR, we captured full‐length ETR1 in a native‐like membrane environment. Our findings reveal dynamic domain uncoupling and Cu(I)‐induced rigidification, providing the first evidence of metal‐triggered ...
Moritz Lemke, Nils Alexander Lakomek, Georg Groth   +2 more
wiley   +1 more source

Mechanistic basis for inhibition of the extended‐spectrum β‐lactamase GES‐1 by enmetazobactam and tazobactam

FEBS Letters, EarlyView.
Antimicrobial resistance (AMR) is of huge importance, resulting in over 1 million deaths each year. Here, we describe how a new drug, enmetazobactam, designed to help fight resistant bacterial diseases, inhibits a key enzyme (GES‐1) responsible for AMR. Our data show it is a more potent inhibitor than the related tazobactam, with high‐level computation
Michael Beer, Philip Hinchliffe, Marko Hanževački, Christopher R. Bethel, Catherine L. Tooke, Marc W. Van der Kamp, Krisztina M. Papp‐Wallace, Robert A. Bonomo, Stuart Shapiro, Adrian J. Mulholland, James Spencer   +10 more
wiley   +1 more source

Toric partial orders

Transactions of the American Mathematical Society, 2015
We define toric partial orders, corresponding to regions of graphic toric hyperplane arrangements, just as ordinary partial orders correspond to regions of graphic hyperplane arrangements. Combinatorially, toric posets correspond to finite posets under the equivalence relation generated by converting minimal elements into maximal elements, or sources ...
Develin, Mike, Macauley, Matthew, Reiner, Victor   +2 more
openaire   +3 more sources

From lactation to malignancy: A comparison between healthy and cancerous breast gland at single‐cell resolution reveals new issues for tumorigenesis

FEBS Letters, EarlyView.
Single‐cell RNA sequencing reveals an opposite role of SLPI in basal tumors based on metastatic spread, along with shared activation of specific regulons in cancer cells and mature luminal lactocytes, as well as downregulation of MALAT1 and NEAT1 in the latter.
Pietro Ancona, Carlo M. Bergamini, Carlo Ferrari, Stefano Volinia, Nicoletta Bianchi   +4 more
wiley   +1 more source

Using spatial and temporal modeling to visualize the effects of U.S. state issued stay at home orders on COVID-19

Scientific Reports, 2021
Coronavirus disease 2019 dominated and augmented many aspects of life beginning in early 2020. Related research and data generation developed alongside its spread.
Rachel Carroll, Christopher R. Prentice
doaj   +1 more source

Protein kinase FAM20C—when subcellular localization matters

FEBS Letters, EarlyView.
FAM20C is a Golgi‐resident kinase that phosphorylates proteins along the entire secretory pathway. The presence of potential FAM20C substrates in the cytoplasm or nucleus raises the question of how the kinase and its substrates encounter each other. Protein kinases achieve signaling specificity through consensus sequence recognition and subcellular ...
Francesca Noventa, Mauro Salvi
wiley   +1 more source

Revealing the structure of land plant photosystem II: the journey from negative‐stain EM to cryo‐EM

FEBS Letters, EarlyView.
Advances in cryo‐EM have revealed the detailed structure of Photosystem II, a key protein complex driving photosynthesis. This review traces the journey from early low‐resolution images to high‐resolution models, highlighting how these discoveries deepen our understanding of light harvesting and energy conversion in plants.
Roman Kouřil
wiley   +1 more source