Results 71 to 80 of about 103,228 (266)
Calpain small subunit homodimerization is robust and calcium‐independent
Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy +4 more
wiley +1 more source
Structural insights into an engineered feruloyl esterase with improved MHET degrading properties
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa +5 more
wiley +1 more source
Diversity and complexity in neural organoids
Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley +1 more source
Continuity in Partially Ordered Sets [PDF]
The notion of a continuous domain is generalized to include posets which are not dcpos and in which the set of elements way below an element is not necessarily directed. We show that several of the pleasing algebraic and topological properties of domains carry over to this setting.
openaire +2 more sources
An isoform of 14‐3‐3 protein regulates transbilayer lipid movement at the plasma membrane
Loss of 14‐3‐3ζ in CHO cells confers resistance to exogenous phosphatidylserine (PS) and impairs endocytosis‐independent inward flip‐flop of fluorescent PS at the plasma membrane. RNAi‐mediated knockdown reproduces this defect, while no additive effect is seen in ATP11C‐deficient cells.
Akiko Yamaji‐Hasegawa +3 more
wiley +1 more source
Reaction kinetics for the oxidation of propane over diluted-leached MoVTeNb is described. This paper is focused on the study of determination of the orders of carbon dioxide, acetic acid and acrylic acid formation.
Restu Kartiko Widi
doaj +1 more source
Embryo‐like structures (stembryos) are an innovative tool, but they are hindered by experimental variability and limited developmental potential. DNA methylation is crucial for mammalian development, but its status in stembryo models is poorly characterized.
Sara Canil +4 more
wiley +1 more source
Dini’s Theorem for Fuzzy Number-Valued Continuous Functions
This work aims to provide several versions of Dini’s theorem for fuzzy number-valued continuous functions defined on a compact set K. In this context, there is a wide variety of possibilities since, unlike the real line, we can consider different ...
Juan José Font +2 more
doaj +1 more source
On the geometric structure of characteristic vector fields related with nonlinear equations of the Hamilton-Jacobi type [PDF]
The Cartan-Monge geometric approach to the characteristics method for Hamilton-Jacobi type equations and nonlinear partial differential equations of higher orders is analyzed.
Natalia K. Prykarpatska +1 more
doaj
In this paper, we introduce the weak group inverse (called as the WG inverse in the present paper) for square complex matrices of an arbitrary index, and give some of its characterizations and properties.
Wang Hongxing, Chen Jianlong
doaj +1 more source

