Results 81 to 90 of about 983,168 (284)
An isoform of 14‐3‐3 protein regulates transbilayer lipid movement at the plasma membrane
FEBS Letters, EarlyView.Loss of 14‐3‐3ζ in CHO cells confers resistance to exogenous phosphatidylserine (PS) and impairs endocytosis‐independent inward flip‐flop of fluorescent PS at the plasma membrane. RNAi‐mediated knockdown reproduces this defect, while no additive effect is seen in ATP11C‐deficient cells.
Akiko Yamaji‐Hasegawa +3 more
wiley +1 more source
Extending Utility Representations of Partial Orders
, 2005 The problem is considered as to whether a monotone function defined on a subset P of a Euclidean space can be strictly monotonically extended to the whole space. It is proved that this is the case if and only if the function is {\em separably increasing}.
Chebotarev, Pavel
core
Partial Symbol Ordering Distance
, 2009 Nowadays sequences of symbols are becoming more important, as they are the standard format for representing information in a large variety of domains such as ontologies, sequential patterns or non numerical attributes in databases. Therefore, the development of new distances for this kind of data is a crucial need.
Herranz Sotoca, Javier +1 more
openaire +2 more sources
AAA+ protein unfoldases—the Moirai of the proteome
FEBS Letters, EarlyView.AAA+ unfoldases are essential molecular motors that power protein degradation and disaggregation. This review integrates recent cryo‐electron microscopy (cryo‐EM) structures and single‐molecule biophysical data to reconcile competing models of substrate translocation.
Stavros Azinas, Marta Carroni
wiley +1 more source
Open Mathematics, 2018 In this paper, we introduce the weak group inverse (called as the WG inverse in the present paper) for square complex matrices of an arbitrary index, and give some of its characterizations and properties.
Wang Hongxing, Chen Jianlong
doaj +1 more source
Fractional-Order Chaotic Memory with Wideband Constant Phase Elements
Entropy, 2020 This paper provides readers with three partial results that are mutually connected. Firstly, the gallery of the so-called constant phase elements (CPE) dedicated for the wideband applications is presented.
Jiri Petrzela
doaj +1 more source
Molecular Oncology, EarlyView.Etoposide induces DNA damage, activating p53‐dependent apoptosis via caspase‐3/7, which cleaves PARP1. Dammarenediol II enhances this apoptotic pathway by suppressing O‐GlcNAc transferase activity, further decreasing O‐GlcNAcylation. The reduction in O‐GlcNAc levels boosts p53‐driven apoptosis and influences the Akt/GSK3β/mTOR signaling pathway ...
Jaehoon Lee +8 more
wiley +1 more source
Molecular Oncology, EarlyView.Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat +8 more
wiley +1 more source
On the geometric structure of characteristic vector fields related with nonlinear equations of the Hamilton-Jacobi type [PDF]
Opuscula Mathematica, 2007 The Cartan-Monge geometric approach to the characteristics method for Hamilton-Jacobi type equations and nonlinear partial differential equations of higher orders is analyzed.
Natalia K. Prykarpatska +1 more
doaj
Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment
Molecular Oncology, EarlyView.This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley +1 more source