Results 81 to 90 of about 978,804 (276)

Substrate specificity of Burkholderia pseudomallei multidrug transporters is influenced by the hydrophilic patch in the substrate‐binding pocket

open access: yesFEBS Letters, EarlyView.
Multidrug transporters BpeB and BpeF from the Gram‐negative pathogen Burkholderia pseudomallei have a hydrophilic patch in their substrate‐binding pocket. Drug susceptibility tests and growth curve analyses using an Escherichia coli recombinant expression system revealed that the hydrophilic patches of BpeB and BpeF are involved in the substrate ...
Ui Okada, Satoshi Murakami
wiley   +1 more source

Mechanisms of parasite‐mediated disruption of brain vessels

open access: yesFEBS Letters, EarlyView.
Parasites can affect the blood vessels of the brain, often causing serious neurological problems. This review explains how different parasites interact with and disrupt these vessels, what this means for brain health, and why these processes matter. Understanding these mechanisms may help us develop better ways to prevent or treat brain infections in ...
Leonor Loira   +3 more
wiley   +1 more source

Classification of (3+1)D Bosonic Topological Orders: The Case When Pointlike Excitations Are All Bosons

open access: yesPhysical Review X, 2018
Topological orders are new phases of matter beyond Landau symmetry breaking. They correspond to patterns of long-range entanglement. In recent years, it was shown that in 1+1D bosonic systems, there is no nontrivial topological order, while in 2+1D ...
Tian Lan, Liang Kong, Xiao-Gang Wen
doaj   +1 more source

On Stable embeddability of partitions

open access: yes, 2005
Several natural partial orders on integral partitions, such as the embeddability, the stable embeddability, the bulk embeddability and the supermajorization, raise in the quantum computation, bin-packing and matrix analysis.
Kim, Dongseok, Lee, Jaeun
core   +1 more source

Time after time – circadian clocks through the lens of oscillator theory

open access: yesFEBS Letters, EarlyView.
Oscillator theory bridges physics and circadian biology. Damped oscillators require external drivers, while limit cycles emerge from delayed feedback and nonlinearities. Coupling enables tissue‐level coherence, and entrainment aligns internal clocks with environmental cues.
Marta del Olmo   +2 more
wiley   +1 more source

In situ molecular organization and heterogeneity of the Legionella Dot/Icm T4SS

open access: yesFEBS Letters, EarlyView.
We present a nearly complete in situ model of the Legionella Dot/Icm type IV secretion system, revealing its central secretion channel and identifying new components. Using cryo‐electron tomography with AI‐based modeling, our work highlights the structure, variability, and mechanism of this complex nanomachine, advancing understanding of bacterial ...
Przemysław Dutka   +11 more
wiley   +1 more source

Natural Transform Decomposition Method for Solving Fractional-Order Partial Differential Equations with Proportional Delay

open access: yesMathematics, 2019
In the present article, fractional-order partial differential equations with proportional delay, including generalized Burger equations with proportional delay are solved by using Natural transform decomposition method.
Rasool Shah   +4 more
doaj   +1 more source

Partial orders on partial isometries [PDF]

open access: green, 2016
Stephan Ramon Garcia   +2 more
openalex   +1 more source

Structural instability impairs function of the UDP‐xylose synthase 1 Ile181Asn variant associated with short‐stature genetic syndrome in humans

open access: yesFEBS Letters, EarlyView.
The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li   +2 more
wiley   +1 more source

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