Results 31 to 40 of about 589,585 (261)

Structural instability impairs function of the UDP‐xylose synthase 1 Ile181Asn variant associated with short‐stature genetic syndrome in humans

FEBS Letters, EarlyView.
The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li, Pedro A. Sánchez‐Murcia, Bernd Nidetzky   +2 more
wiley   +1 more source

Transferrin receptor 1‐mediated iron uptake supports thermogenic activation in human cervical‐derived adipocytes

FEBS Letters, EarlyView.
In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai, Mizuki Seo, Gyath Karadsheh, Fachrur Rizal Mahendra, Máté Á Demény, Ferenc Győry, János András Mótyán, László Fésüs, Endre Kristóf, Rini Arianti   +9 more
wiley   +1 more source

Imputation of arterial oxygen partial pressures using pulse oximetry in surgical patients under general anaesthesia: A prospective cohort study

Indian Journal of Anaesthesia
Background and Aims: Monitoring oxygen saturation (SpO2) during general anaesthesia using pulse oximetry is mandatory, though it may not always reflect the actual oxygenation status.
Mohamad F. El-Khatib, Marwan Rizk, Amro Khalili, Thuraya HajAli, Ibrahim El Mallah, Rasha Shreim, Carine Zeeni   +6 more
doaj   +1 more source

Preparation and Characterization of NiO Thin Films by DC Reactive Magnetron Sputtering [PDF]

Журнал нано- та електронної фізики, 2012
Nickel oxide (NiO) thin films were successfully deposited on Corning 7059 glass substrates at different oxygen partial pressures in the range of 1 × 10 – 4 to 9 × 10 – 4 mbar using dc reactive magnetron sputtering technique.
Y. Ashok Kumar Reddy, A. Mallikarjuna Reddy, A. Sivasankar Reddy, P. Sreedhara Reddy   +3 more
doaj  

Effect of CO₂ Partial Pressure on the Corrosion Behavior of S135 Steel in CO₂/H₂S Coexistence Systems [PDF]

Cailiao Baohu
In order to clarify the influence and regularity of CO2 partial pressure on the corrosion behavior of S135 steel in the CO2/H2S coexistence system， the corrosion simulation test of S135 steel in CO2/H2S coexistence systems was conducted by using ...
GAO Kechao, SHANG Suogui, GAO Qiangyong, MA Jinxin, ZHANG Zhi, LIU Wanying
doaj   +1 more source

Calpain small subunit homodimerization is robust and calcium‐independent

FEBS Letters, EarlyView.
Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy, Trina Dykstra‐MacPherson, Mathias A. Bell, Peter L. Davies, Ruby May A. Sullan   +4 more
wiley   +1 more source

Effects of Oxygen Partial Pressure on 4-Hydroxy-2-Nonenal Induced Oxymyoglobin Oxidation

Meat and Muscle Biology, 2019
4-hydroxyl-2-nonenal (HNE) is a lipid oxidation product that can increase oxymyoglobin oxidation. However, limited research has evaluated the role of oxygen partial pressure in HNE-induced metmyoglobin formation.
Deborah L. VanOverbeke, Frank Kiyimba, Gretchen Mafi, Janet Rogers, Mahesh N. Nair, Ranjith Ramanathan, Steven D. Hartson, Thiago S. Belem   +7 more
doaj   +2 more sources

Structural insights into an engineered feruloyl esterase with improved MHET degrading properties

FEBS Letters, EarlyView.
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa, Konstantinos Makryniotis, Theofani‐Iosifina Sousani, Evangelos Topakas, Vangelis Daskalakis, Maria Dimarogona   +5 more
wiley   +1 more source

Correlação entre as pressões parciais de co2 no ar expirado e no sangue arterial, em porcas submetidas a pneumoperitônio

Revista do Colégio Brasileiro de Cirurgiões
OBJETIVO: As cirurgias realizadas por via laparoscópica, que utilizam CO2 para realização do pneumoperitônio, cursam com hipercarbia. Esta alteração pode ser estimada pela pressão parcial de CO2 no ar expirado.
Antonio Carlos Valezi, Jorge Mali Junior, Rodrigo Gomes de Oliveira, Laerte H. Storti   +3 more
doaj   +1 more source

Research on Contact Pressure Distribution of Pad

MATEC Web of Conferences, 2018
A simplified thermo-structural coupling finite element model of disc brake was developed. The contact pressure distribution of new pad was simulated under an emergency braking condition.
Chen Dong, Zou Guofeng
doaj   +1 more source