An identity for ordered partial sums
openaire +3 more sources
Drug resistance limits treatment success in a subset of lung cancers driven by ROS1 gene alterations. Using patient‐derived cells and computer simulations, we studied three key mutations and how they affect five targeted drugs. The mutations reduced drug effectiveness in different ways by altering protein structure and behavior.
Farhan Ul Haq +8 more
wiley +1 more source
Clinical activity of chidamide-containing regimens after prior PD-1-based therapy in two patients with microsatellite-stable metastatic colorectal cancer: a case series and narrative review. [PDF]
Chen R, Yang D, Xu H.
europepmc +1 more source
Cancer‐associated mutations in endometriosis reframe a benign disease through molecular oncology
This review aims to comprehensively analyse cancer‐associated somatic mutations (CAMs) present in endometriotic lesions, emphasizing their biological roles, spatial distribution and implications for translational applications in medicine. By contextualizing a benign state within a genomic framework, this analysis seeks to establish its value as a ...
Clarissa Mujacic +15 more
wiley +1 more source
On the Partial Sum of Subword-Counting Sequences
Let $w$ be a finite word over the alphabet $\{0,1\}$. For any natural number $n$, let $s_w(n)$ denote the number of occurrence of $w$ in the binary expansion of $n$ as a scattered subsequence.
Li, Shuo, Jain, Pranjal
core
The impact of reward scalarization and weight scheduling on optimization dynamics in multi-objective molecular design. [PDF]
Leuschner L, Palomino-Hernandez O.
europepmc +1 more source
Detecting circulating tumor cells (CTCs) in blood before surgery may help predict outcomes in patients with head and neck squamous cell carcinoma (HNSCC). Here, we show when combined with tumor size and lymph node involvement from routine imaging, CTC status identifies high‐risk patients with poorer survival—offering a simple, minimally invasive tool ...
Susanne Flach +9 more
wiley +1 more source
Dark-State-Mediated Low-Energy Electron Attachment to Molecular Oxygen: Symmetry Adapted Decomposition of the DEA Resonance through Dyson-Orbitals' Incoherent Mixing. [PDF]
Kundu N +4 more
europepmc +1 more source
Tumour heterogeneity and clonal evolution of metastatic salivary gland cancer were evaluated in two patients with adenoid carcinoma and one patient with myoepithelial carcinoma. Radiology‐guided autopsy enabled multi‐region sampling (total samples n = 149), followed by whole‐genome sequencing and phylogenetic reconstruction (17 tumour samples, 4–7 per ...
Gerben Lassche +10 more
wiley +1 more source
Globalization of Perturbative Chern-Simons Theory on the Moduli Space of Flat Connections in the BV Formalism. [PDF]
Mnev P, Wernli K.
europepmc +1 more source

