Results 101 to 110 of about 665,193 (301)

Detecting homologous recombination deficiency for breast cancer through integrative analysis of genomic data

open access: yesMolecular Oncology, EarlyView.
This study develops a semi‐supervised classifier integrating multi‐genomic data (1404 training/5893 validation samples) to improve homologous recombination deficiency (HRD) detection in breast cancer. Our method demonstrates prognostic value and predicts chemotherapy/PARP inhibitor sensitivity in HRD+ tumours.
Rong Zhu   +12 more
wiley   +1 more source

Coupled fixed point results for $alpha$-admissible Mizoguchi-Takahashi contractions in $b$-metric spaces with applications [PDF]

open access: yesSahand Communications in Mathematical Analysis, 2017
The aim of this paper is to  establish some fixed point theorems for $alpha$-admissible Mizoguchi-Takahashi contractive mappings defined on a ${b}$-metric space which generalize the results of Gordji and Ramezani cite{Roshan6}.
Vahid Parvaneh   +3 more
doaj  

On lattice of Basic Z-Ideals

open access: yesپژوهش‌های ریاضی, 2021
For an f-ring  with bounded inversion property, we show that  , the set of all basic z-ideals of , partially ordered by inclusion is a bounded distributive lattice.
Ali Taherifar
doaj  

Data‐driven discovery of gene expression markers distinguishing pediatric acute lymphoblastic leukemia subtypes

open access: yesMolecular Oncology, EarlyView.
This study investigates gene expression differences between two major pediatric acute lymphoblastic leukemia (ALL) subtypes, B‐cell precursor ALL, and T‐cell ALL, using a data‐driven approach consisting of biostatistics and machine learning methods. Following analysis of a discovery dataset, we find a set of 14 expression markers differentiating the ...
Mona Nourbakhsh   +8 more
wiley   +1 more source

GCD matrices, posets, and nonintersecting paths

open access: yes, 2004
We show that with any finite partially ordered set one can associate a matrix whose determinant factors nicely. As corollaries, we obtain a number of results in the literature about GCD matrices and their relatives.
Altinisik, Ercan   +2 more
core   +1 more source

MicroRNA 196a contributes to the aggressiveness of esophageal adenocarcinoma through the MYC/TERT/NFκB axis

open access: yesMolecular Oncology, EarlyView.
mir‐196a promotes Esophagus Adenocarcinoma aggressiveness. On one hand, mir‐196a targets the valosin‐containing protein (VCP) mRNA, causing the accumulation of c‐MYC protein that leads to high amounts of TERT. On the other hand, mir‐196a targets the inhibitor of NFκB (NFKBIA).
Jesús García‐Castillo   +8 more
wiley   +1 more source

A Discrete Dynamical Model of Signed Partitions

open access: yesJournal of Applied Mathematics, 2013
We use a discrete dynamical model with three evolution rules in order to analyze the structure of a partially ordered set of signed integer partitions whose main properties are actually not known.
G. Chiaselotti   +3 more
doaj   +1 more source

Comprehensive omics‐based classification system in adult patients with B‐cell acute lymphoblastic leukemia

open access: yesMolecular Oncology, EarlyView.
The COMBAT classification system, developed through multi‐omics integration, stratifies adult patients with B‐cell acute lymphoblastic leukemia(B‐ALL) into three molecular subtypes with distinct surface antigen patterns, immune landscape, methylation patterns, biological pathways and prognosis.
Yang Song   +11 more
wiley   +1 more source

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