FEBS Letters, EarlyView.We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee +3 more
wiley +1 more source
Implementing an Oral Health Intervention for People Experiencing Homelessness in Scotland: A Participant Observation Study. [PDF]
Dent J (Basel), 2018 Beaton L +4 more
europepmc +1 more source
Structural biology of ferritin nanocages
FEBS Letters, EarlyView.Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley +1 more source
Les pratiques de terrain en situation de tensions sociales et de guerre civile au Congo-Brazzaville
Sociologies, 2011 Referring to my own field practices in a situation of social tension and civil war in Congo-Brazzaville entails a genuine critical examination of a society which is at the same time a social world made up of a plurality of social microcosms and the field
Abel Kouvouama
doaj
β‐TrCP overexpression enhances cisplatin sensitivity by depleting BRCA1
Molecular Oncology, EarlyView.Low levels of β‐TrCP (Panel A) allow the accumulation of BRCA1 and CtIP, which facilitate the repair of cisplatin‐induced DNA damage via homologous recombination (HR) and promote tumor cell survival. In contrast, high β‐TrCP expression (Panel B) leads to BRCA1 and CtIP degradation, impairing HR repair, resulting in persistent DNA damage and apoptosis ...
Rocío Jiménez‐Guerrero +8 more
wiley +1 more source
Focused Ethnography: A Methodological Adaptation for Social Research in Emerging Contexts
Forum: Qualitative Social Research, 2014 Ethnography is one of the oldest qualitative methods, yet increasingly, researchers from various disciplines are using and adapting ethnography beyond its original intents.
Sarah Stahlke Wall
doaj
Enabling At-Homeness for Older People With Life-Limiting Conditions: A Participant Observation Study From Nursing Homes. [PDF]
Glob Qual Nurs Res, 2019 Saarnio L +4 more
europepmc +1 more source
Molecular Oncology, EarlyView.AZD9291 has shown promise in targeted cancer therapy but is limited by resistance. In this study, we employed metabolic labeling and LC–MS/MS to profile time‐resolved nascent protein perturbations, allowing dynamic tracking of drug‐responsive proteins. We demonstrated that increased NNMT expression is associated with drug resistance, highlighting NNMT ...
Zhanwu Hou +5 more
wiley +1 more source
Experimental Archaeology as Participant Observation: A Perspective from Medieval Food
EXARC Journal, 2017 Central to anthropology is the concept of participant observation, where a researcher engages in immersive learning through ethnographic fieldwork. This concept is also important for archaeologists as immersive learning provides an avenue for more robust
Scott D. Stull
doaj
How are decisions made in cancer care? A qualitative study using participant observation of current practice. [PDF]
BMJ Open, 2017 Hahlweg P +3 more
europepmc +1 more source