Results 121 to 130 of about 67,524,308 (281)

Participatory community Action Research process addressing employment integration of internationally trained professionals (ITPs) in Canada

, 2016
This paper describes the use of a community action research process (CARP) to understand the lived experiences of internationally trained professionals’ (ITPs) unemployment and underemployment in a Community-Based Participatory Action Research (CBPAR ...
Chiu, Yvonne, Khalema, Nene Ernest, Ortiz, Lucenia, Shankar, Janki, Zulla, Rosslyn   +4 more
core  

Comparing the paths of Hedgehog release in artificial and natural settings

FEBS Letters, EarlyView.
Hh morphogens require solubilization factors to overcome their tight association with the plasma membrane and signal to distant cells, but the precise functions of these factors are controversial. Here, we use published in vivo observations as the most relevant evidence to test their suggested functions and discuss contradictions and gaps between in ...
Janna Puschmann, Kay Grobe
wiley   +1 more source

Editorial: Action Research (May 2019)

Technology Innovation Management Review, 2019
Chris McPhee, Magnus Hoppe, Erik Lindhult   +2 more
doaj   +1 more source

Participatory Action Research: Engaging Communities in Mental Health

MedUNAB
As we usher in the new year, it presents a valuable opportunity for introspection and forward-looking aspiration an invitation to envision a future enriched with hope and an improved quality of life. While personal reflections often take center stage, it
Sandra Janashak, Cadena
doaj   +1 more source

How structural disorder and polyelectrolyte properties of prothymosin α enable its large interactome

FEBS Letters, EarlyView.
In this review, complexes of the fully disordered and highly negatively charged prothymosin α are collected, described, and discussed. Linked to its poly‐electrostatic character, prothymosin α engages a large interactome through multiple different binding modes ranging from fully disordered complexes to short linear motif (SLiM)‐driven interactions ...
Ketty C. Tamburrini, Freia S. Buus, Benjamin Schuler, Birthe B. Kragelund   +3 more
wiley   +1 more source

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

Molecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Participatory research and action in India [PDF]

, 1989
Where does participatory research stand today in India? To understand this, one needs to see where participatory action stands today; because a genuinely participatory approach to research has to be a response to action.
Fernandes, Walter
core  

Hijacking emergency granulopoiesis: Neutrophil ontogeny and reprogramming in cancer

Molecular Oncology, EarlyView.
Neutrophils are highly plastic innate immune cells; their functions in cancer extend beyond the tumour microenvironment. This Review summarises current understanding of neutrophil maturation and heterogeneity and highlights tumour‐induced granulopoiesis as a systemic programme that expands immature, immunosuppressive neutrophils via tumour‐derived ...
Gabriela Marinescu, Yi Feng
wiley   +1 more source

Youth Participatory Action Research for Equitable Urban Design

Journal of Participatory Research Methods
The Nashville Youth Design Team (NYDT) is a youth participatory action research and design collective based in Metro Nashville-Davidson County, Tennessee, USA.
Kayla M. Anderson, Megan L. McCormick, Kathryn Y. Morgan, Melody Gibson, Addison Harper, Mia Clark, Brian D. Christens   +6 more
doaj   +1 more source

Inhibition of cyclin‐dependent kinases 12/13 using CT7439 as a treatment for colorectal cancer with CDK12 upregulation

Molecular Oncology, EarlyView.
The proposed mechanism of action for the CDK12/13 inhibitor and cyclin K degrader, CT7439. CDK12/13 inhibition interrupts transcription elongation, leading to increased DNA damage that results in cell death. This agent is a potentially novel treatment option for patients with colorectal cancer. Created in BioRender. Cyclin‐dependent kinase (CDK) 12 and
Wylie K. Watlington, Divya L. Dayanidhi, Mohammad Zokaasadi, John B. Mantyh, Pelumi D. Olawuni, Gabrielle Rupprecht, Jeremy M. Force, Shannon McCall, Ashwani K. Bahl, David S. Hsu, Jason A. Somarelli   +10 more
wiley   +1 more source