Results 141 to 150 of about 67,524,308 (281)

Engaging the practice of Indigenous yarning in Action Research

, 2011
This paper discusses the technique of ‘yarning’ as an action research process relevant for policy development work with Aboriginal peoples. Through a case study of an Aboriginal community-based smoking project in the Australian State of Victoria, the ...
Fredericks, Bronywn, Adams, Karen
core  

Regulation of the lncRNA NEAT1 by p53‐ΔNp63 crosstalk modulates the DNA damage response and therapeutic efficacy in HNSCC

Molecular Oncology, EarlyView.
In head and neck squamous cell carcinoma (HNSCC) p53 and p63 exert opposite roles on the transcription regulation of the lncRNA NEAT1. Under basal conditions, p53 levels are low and p63 represses NEAT1 expression. Upon genotoxic stress, p53 is rapidly induced, displacing p63 from the NEAT1 promoter leading to NEAT1 transcriptional activation and ...
Sara De Domenico, Veronica La Banca, Silvia D'Amico, Stefano Scalera, Sara Nicolai, Angelo Peschiaroli   +5 more
wiley   +1 more source

Participatory action research in rural and vulnerable settings for community health: a systematic literature review. [PDF]

BMC Public Health
Carmena Del Viso M, Beni-Abdellah U, Moradell A, Navas-Ferrer C, Blázquez-Ornat I, Raimundo A, Kalkan I, Antón-Solanas I, Iguacel I, Navarrete-Villanueva D.   +9 more
europepmc   +1 more source

Doing participatory evaluation in Indigenous contexts

, 2013
In countering the legacies of colonisation, aboriginal communities across Canada are beginning to mount their own locally inspired and developed initiatives in business, health, welfare and education to address needs that they have identified. This paper
Mark, Rodney, Stocek, Christine, Jordan, Steve   +2 more
core  

Extracellular matrix remodeling and immune reprogramming drive residual tumor progression of liver cancer after incomplete microwave ablation

Molecular Oncology, EarlyView.
Incomplete microwave ablation (iMWA) of liver cancer triggers a biphasic progression in residual tumors. At Day 3, the microenvironment is characterized by acute inflammatory responses and extracellular matrix (ECM) remodeling. By Day 14, a profound shift occurs toward oncogenic signal transduction and immunosuppression, marked by macrophage ...
Yu Liu, Yubei He, Nikolaus Berndt, Michael Mülleder, Kathrin Textoris‐Taube, Jing Guo, Matthias Stechele, Justus Ramtke, Shraga Nahum Goldberg, Lynn Jeanette Savic   +9 more
wiley   +1 more source

Participatory Action Research: Meaningful Student Involvement in Medical Curriculum Development. [PDF]

Clin Teach
Tyson Y, Al-Jawad M.
europepmc   +1 more source

Unique circulating miRNAome signatures captured with distinct molecular states in Lynch syndrome and sporadic colorectal cancer

Molecular Oncology, EarlyView.
Circulating microRNA profiles distinguish nonmalignant Lynch syndrome from cancer‐associated Lynch syndrome, sporadic colorectal cancer, and healthy controls. Age‐stratified analysis reveals disease‐specific regulatory states, and a six‐miRNA panel shows concordant separation in an independent colorectal tissue cohort.
Ramadhani Salum Chambuso, Md Shohel Ul Islam, Rosa M Xicola, Raj Ramesar, Xavier Llor, Sinclair Steele   +5 more
wiley   +1 more source

Action Research and Development for Intrinsic Innovation in Social Service Administration: Prototyping and Proof of Concept in Small Scale Start-Ups

, 2013
In considering the significance of the small-scale start-up in social service agencies and community development, the authors address how community-based participatory action research can serve as an innovation strategy in social service administration ...
Moxley, David P., Thompson, Valerie R., Deacon, Zermarie   +2 more
core  

SPHINX31 acts as a SRPK1 inhibitor targeting the ATR/DNA‐PKcs/CHK1 replicative checkpoint to inhibit cell growth in non‐small cell lung cancer

Molecular Oncology, EarlyView.
The kinase SRPK1 directly interacts with the protein TOPBP1 and regulates the pre‐mRNA splicing of WIZ thereby contributing to the activation of the ATR/CHK1 replicative checkpoint in response to replicative stress. This allows cancer cells' genomic stability and survival.
Amani Shreim, Aurelie Genoux, Nadiia Zubchuk, Haoyang Zheng, Perla Salameh, Theo Ziegelmeyer, Fabien Dalonneau, Margot Rouchette, Christiane Oddou, Simona Miron, Helene Polveche, Adiilah Mamode Cassim, Carmen Garrido, Eleni Nikolakaki, Didier Auboeuf, Tao Jia, Sophie Zinn‐Justin, Beatrice Eymin   +17 more
wiley   +1 more source

Participatory Action Research in Health Promotion in the Philippines: A Scoping Review. [PDF]

Acta Med Philipp
Famaloan FRAN, Alvina KC, Ong LAD, Antonio CAT, Reyes KAV.   +4 more
europepmc   +1 more source