Results 161 to 170 of about 84,797 (291)

Guiding AlphaFold to predict how Munc13‐1 opens Syntaxin‐1

FEBS Open Bio, EarlyView.
The syntaxin‐1 Habc‐domain (orange), linker (pink) and SNARE motif (yellow) form a closed conformation that binds to Munc18‐1 (violet) and is opened by the Munc13‐1 MUN domain (cyan) to form the SNARE complex that triggers neurotransmitter release.
Madhurima Chattopadhyay, Junjie Xu, Josep Rizo   +2 more
wiley   +1 more source

Three days inside: exploring reciprocity and trust in a participatory action research community case study in the Netherlands. [PDF]

Front Public Health
Dalstra L, Jepkema N, Jeschke AM, Hofenk H, Broekhuizen J, Van Der Lucht F.   +5 more
europepmc   +1 more source

Action Research and Development for Intrinsic Innovation in Social Service Administration: Prototyping and Proof of Concept in Small Scale Start-Ups

, 2013
In considering the significance of the small-scale start-up in social service agencies and community development, the authors address how community-based participatory action research can serve as an innovation strategy in social service administration ...
Moxley, David P., Thompson, Valerie R., Deacon, Zermarie   +2 more
core  

Small RNA pathways in mammalian oocytes

FEBS Open Bio, EarlyView.
Three distinct small RNA pathways operate in mammalian oocytes: RNAi interference (RNAi), the microRNA (miRNA) pathway, and the PIWI‐associated RNA (piRNA) pathway. These pathways use small RNAs to guide sequence‐specific repression and contribute to oocyte biology by targeting genes and mobile elements or appear insignificant since different ...
Petr Svoboda, Josef Pasulka
wiley   +1 more source

Improving Family-Centred Care in Intensive Care Units: Participatory Action Research to Design and Implement Changes in Nursing Care. [PDF]

Nurs Crit Care
de la Cueva-Ariza L, Delgado-Hito P, Lluch-Canut MT, Momblan MAM, Benito-Aracil L, Via-Clavero G, Cabellos CC, Romero-García M.   +7 more
europepmc   +1 more source

Engaging Indigenous Youth in Community-Based Participatory Action Research: A Scoping Review

, 2019
Community-based participatory action research (CBPAR) frameworks are becoming a leading strategy for conducting research with Indigenous communities and youth.
Hackett, Lisa
core  

How phagocytic cells kill bacteria: Lessons from a professional killer

FEBS Open Bio, EarlyView.
How phagocytic cells ingest and kill bacteria has been studied for more than a century, but many questions remain unanswered. The study of the amoeba Dictyostelium discoideum brings new answers, and new questions. Professional phagocytic cells such as neutrophils and macrophages, as well as free‐living soil amoebae like Dictyostelium discoideum, employ
Otmane Lamrabet, Pierre Cosson
wiley   +1 more source

Moving from "damage-centered" research to "family-centered" participatory action research for systems change: a call to action for developmental and family scientists. [PDF]

Front Psychol
Vesely CK, Letiecq BL, Zhang X, Family Council for Equity in Education.   +3 more
europepmc   +1 more source

Introduction to Conferences as Sites of Learning and Development: Using participatory action learning and action research approaches

, 2017
This chapter introduces the main aims of this book, namely to apply and expand upon the concept of the ‘learning conference’ as a site of learning and development, using the paradigm and methodologies of participatory action learning and action research (
Zuber-Skerritt, Ortrun
core  

Effects of IGFBP4 deficiency on human preadipocyte proliferation and differentiation through the IGF1R/AKT pathway

FEBS Open Bio, EarlyView.
IGFBP4 knockdown (KD) impairs preadipocyte proliferation and is associated with IGF1R protein downregulation and attenuated AKT phosphorylation. The mechanisms by which IGFBP4 KD influences the IGF1R/AKT signaling pathway involve newly synthesized proteins and lysosomal degradation pathways. Created in BioRender.
Yujia Guo, Sandy Richter, Christoph Bach, Wieland Kiess, Anna Kirstein, Diana Le Duc, Antje Garten   +6 more
wiley   +1 more source