Results 101 to 110 of about 4,314,651 (296)
Molecular Oncology, EarlyView.In head and neck squamous cell carcinoma (HNSCC) p53 and p63 exert opposite roles on the transcription regulation of the lncRNA NEAT1. Under basal conditions, p53 levels are low and p63 represses NEAT1 expression. Upon genotoxic stress, p53 is rapidly induced, displacing p63 from the NEAT1 promoter leading to NEAT1 transcriptional activation and ...
Sara De Domenico +5 more
wiley +1 more source
#Medieval: “First World” medievalism and participatory culture
, 2021 Habermas’ identification of a ‘public sphere’ as a democratic, open, and fundamentally participatory space is often identified as the emergence of a kind of modern political consciousness1. Given its identification within the seventeenth and eighteenth centuries it thus emerges as a modern invention to be contrasted against the implied feudalism of the
openaire +2 more sources
CFP: Fan CULTure: An Examination of Participatory Fandom in the 21st Century (15 mai)
, 2012 Fan CULTure: An Examination of Participatory Fandom in the 21st Century With the advent of new media technologies and social networking sites making communication faster and easier than ever, there exists a dearth of opportunity to see how fan cultures ...
Irène Langlet
core
Molecular Oncology, EarlyView.The kinase SRPK1 directly interacts with the protein TOPBP1 and regulates the pre‐mRNA splicing of WIZ thereby contributing to the activation of the ATR/CHK1 replicative checkpoint in response to replicative stress. This allows cancer cells' genomic stability and survival.
Amani Shreim +17 more
wiley +1 more source
“No Geek Girls”: Boundary-Work and Gendered Identity in the Israeli Geek Community
International Journal of Communication, 2022 Boundary-work theory describes the discursive efforts of groups to limit access to membership and collective symbolic capital. In this article, we explore the gendered nature of boundary-work within an online community of Geeks—a subcultural identity ...
Hadas Gur-Ze'ev, Neta Kligler-Vilenchik
doaj
Molecular Oncology, EarlyView.LVRF (lymphatic and vascular resistance factor) is a VEGFA splice variant upregulated in response to anti‐angiogenic therapy that fosters tumor adaptation through enhanced vascularization, lymphangiogenesis, and metastatic dissemination. Targeting LVRF with fully human neutralizing antibodies disrupts these processes and limits resistant tumor growth ...
Marion David +12 more
wiley +1 more source
Attitudes of cancer patients toward ctDNA‐based liquid biopsy for follow‐up
Molecular Oncology, EarlyView.This mixed‐methods study explored cancer patients' experiences, knowledge, and preferences regarding ctDNA‐based liquid biopsy for follow‐up. Awareness of ctDNA was low and recall of previous liquid biopsy was imperfect, yet acceptance was high.
Siddharth Chhajlani +7 more
wiley +1 more source
Global StorytellingAlthough fan cultures highlighting active audience engagement is prevalent in East Asia, the process and impact of such engagement have not been thoroughly explored in the literature.
BU Jiahua
doaj +2 more sources
FEBS Open Bio, EarlyView.IGFBP4 knockdown (KD) impairs preadipocyte proliferation and is associated with IGF1R protein downregulation and attenuated AKT phosphorylation. The mechanisms by which IGFBP4 KD influences the IGF1R/AKT signaling pathway involve newly synthesized proteins and lysosomal degradation pathways. Created in BioRender.
Yujia Guo +6 more
wiley +1 more source
Do it Together : Practices and Tendencies of Participatory Governance in Culture in the Republic of Croatia [PDF]
, 2018 This book builds on the results of a two-year project "Approaches to Participatory Governance of Cultural Institutions", which Kultura Nova Foundation implemented with the support of UNESCO International Fund for Cultural Diversity (IFCD), and is ...
Mirko Petri? +4 more
core +1 more source