Results 71 to 80 of about 71,336 (260)

Participatory Design of Websites with Web Design Workshops

open access: yesCode4Lib Journal, 2008
At the University of Rochester's River Campus Libraries we have included users in technology development with great success. "Participatory design" entails collaboration among designers, developers, and users from the earliest stages of conception ...
Alison Bersani   +2 more
doaj  

Script Tales from a Rural Participatory Research Process

open access: yesNordic Journal of Science and Technology Studies
This article critically reflects on a participatory research and co-design process within rural energy transitions, focusing on energy citizenship in the small town of Overhalla in Norway.
Lina Naoroz Bråten   +3 more
doaj   +1 more source

Creating Gameful Design in mHealth: A Participatory Co-Design Approach

open access: yesJMIR mHealth and uHealth, 2018
BackgroundGameful designs (gamification), using design pieces and concepts typically found in the world of games, is a promising approach to increase users’ engagement with, and adherence to, electronic health and mobile health (mHealth) tools.
Jessen, Stian   +2 more
doaj   +1 more source

Investigating transcription factor dynamics in health and disease using FRAP

open access: yesFEBS Letters, EarlyView.
FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj   +3 more
wiley   +1 more source

An Introduction to Radical Biocracy: A relational, autonomous approach to decision-making towards emergent and symbiotic design

open access: yesDesign Science
Any system health work must look at decision-making because decisions propagate throughout a system, shaping system dynamics. Usually, human decision-making is conducted from an individualist, objectivist perspective. What happens when we use an approach
Victor Udoewa
doaj   +1 more source

Conserved binding mode but diverse interfaces of MreC‐PBP2 interactions

open access: yesFEBS Letters, EarlyView.
The crystal structure of abMreC reveals a conserved two β‐barrel architecture and provides structural insights into its role within the bacterial elongasome. The abMreC–abPBP2 complex model identifies the molecular basis of MreC‐mediated PBP2 recognition, contributing to the regulation of peptidoglycan synthesis.
Hyunseok Jang   +4 more
wiley   +1 more source

The role of miR‐335‐5p in the redifferentiation of BRAF p.V600E thyroid cancers

open access: yesMolecular Oncology, EarlyView.
The BRAF p.V600E mutation promotes thyroid cancer dedifferentiation and radioiodine resistance. Using a network approach, we identified miR‐335‐5p as a key regulator of BRAF‐mutated thyroid tumors. Restoring miR‐335‐5p increased thyroid‐specific gene expression and iodine uptake in cells and organoids.
Valeria Pecce   +11 more
wiley   +1 more source

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

open access: yesMolecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

The Platformization of Media Structures as a Critical Juncture

open access: yesMedien & Zeit
The field of digital journalism is facing multifaceted crises posed by the phenomenon of platformization. We interpret this platformization as a critical juncture and investigate how different actors address the associated challenges, focusing on ...
Markus Uhlmann   +4 more
doaj  

Reimagining participatory design [PDF]

open access: yesInteractions, 2018
Liam Bannon   +2 more
openaire   +1 more source

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