Results 81 to 90 of about 9,595,710 (283)

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

FEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

The Platformization of Media Structures as a Critical Juncture

Medien & Zeit
The field of digital journalism is facing multifaceted crises posed by the phenomenon of platformization. We interpret this platformization as a critical juncture and investigate how different actors address the associated challenges, focusing on ...
Markus Uhlmann, Jonathan Kropf, Viktoria Horn, Claude Draude, Jörn Lamla   +4 more
doaj  

Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation

FEBS Letters, EarlyView.
Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz, Mihály Mérey, Rebeka Vásárhelyi, Ramóna Pék, Victor Imburchia, László Henn, Adrián Kószó, Nicholas D. Lakin, Ivan Ahel, Sébastien Huet, Ágnes Czibula, Gyula Timinszky   +11 more
wiley   +1 more source

Reimagining participatory design [PDF]

Interactions, 2018
Liam Bannon, Jeffrey Bardzell, Susanne Bødker   +2 more
openaire   +1 more source

Salmonella lipopolysaccharide‐containing supported lipid bilayers as platforms to study bacteriophage interactions

FEBS Letters, EarlyView.
We present robust protocols for the preparation of supported lipid bilayers (SLBs) incorporating either Salmonella smooth LPS or outer membrane vesicles (OMVs). We use a combination of quartz crystal microbalance with dissipation (QCM‐D) and fluorescence microscopy to both characterize the SLBs of various compositions and to probe their interactions ...
Hudson P. Pace, Alyssa Borges, Charles Arnaud, Tove Karlsson, Nina K. Bröker, Stefanie Barbirz, Marta Bally   +6 more
wiley   +1 more source

Involving Older People in Participatory Action Research: An Example of Participatory Action Design

Romanian Journal of Communications and Public Relations, 2018
Participatory Action Research (PAR) has as a main goal the collaborative construction and production of meanings between the researchers and the participants.
Ioana Schiau, Loredana Ivan, Monica Bîră   +2 more
doaj   +1 more source

Microbiome−host proteostasis crosstalk—An emerging perspective on mechanisms and interventions toward healthy longevity

FEBS Letters, EarlyView.
Proteostasis and the gut microbiota play a key role in shaping host physiology. Microbiota‐derived metabolites, vitamins, and RNA modulate host proteostasis. Findings from model systems, including C. elegans, indicate microbes can either stabilize or disrupt host proteostasis.
Abhishek Anil Dubey, Maria Ermolaeva
wiley   +1 more source

Digitising the Physical: The Evolving Role of Collaboration Tools in Citizen Participatory Design Amidst the COVID-19 Pandemic in Seoul

Temes de Disseny
This case study investigates how the digital transformation of urban design governance following the COVID-19 outbreak has led to changes in approaches to citizen participatory design in Seoul, South Korea.
Oxana Jeoung-Rakova
doaj   +1 more source

More-Than-Human Participatory Design

The ecological crises we face are fed by a disconnect from interspecies interdependencies and misguided human-exceptionalism (the belief we are somehow distinct from nature).
Akama, Yoko,, Lindström, Kristina,, Light, Ann,, Ståhl, Åsa,, Heitlinger, Sara,   +4 more
core   +1 more source

Exploring participatory design for SNS-based AEH systems [PDF]

, 2012
The rapidly emerging and growing social networking sites (SNS) offer an opportunity to improve adaptive e-learning experience by introducing a social dimension, connecting users within the system.
Al Qudah, Dana, Al-Qudah, D, Shi, L, Shi, Lei, Cristea, A, Cristea, Alexandra I.   +5 more
core   +1 more source