Results 91 to 100 of about 1,111,775 (322)

Implementing integrated river basin management: lessons from the Red River Basin, Vietnam [PDF]

River basin management / Water resource management / Legal aspects / Water law / Water policy / Institutional reform / Organizational change / Institutions / Governance / Development projects / Participatory management / Vietnam / Red River Basin / Cau ...
Hoanh, Chu Thai, Molle, Francois
core  

Marginalised or enabled voices? 'User participation' in policy and practice [PDF]

, 2008
The idea of participation has been central to many policy developments in recent years. Both Conservative and Labour governments have used notions of participation and involvement in attempts to justify and implement their social policies. Yet, despite a
Arksey, Bang, Barnes, Beresford, Birchall, Catherine Bochel, Claire Worley, Fung, Gaventa, Halpern, Hugh Bochel, Kooiman, Layard, Massey, Morris, Peter Somerville, Platt, Saward, Skidmore, Stoker   +19 more
core   +1 more source

Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?

FEBS Letters, EarlyView.
This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes, Guilherme M. Azevedo, Amanda P. Barcellos, Diana Bahia   +3 more
wiley   +1 more source

Three tyrannies of participatory governance

Journal of Chinese Governance, 2019
Despite the potential promise of more participatory urban governance, some debates do not sufficiently reflect difficult realities. This paper aims to make good on this by maintaining reflexivity about tensions.
L. Richardson, C. Durose, B. Perry
semanticscholar   +1 more source

Peptide‐based ligand antagonists block a Vibrio cholerae adhesin

FEBS Letters, EarlyView.
The structure of a peptide‐binding domain of the Vibrio cholerae adhesin FrhA was solved by X‐ray crystallography, revealing how the inhibitory peptide AGYTD binds tightly at its Ca2+‐coordinated pocket. Structure‐guided design incorporating D‐amino acids enhanced binding affinity, providing a foundation for developing anti‐adhesion therapeutics ...
Mingyu Wang, Grace Du, Charity Yongo‐Luwawa, Angelina Lu, Brett Kinrade, Kim Munro, Karl E. Klose, William D. Lubell, Peter Davies, Shuaiqi Guo   +9 more
wiley   +1 more source

The deliberative turn in participation: the problem of inclusion and deliberative opportunities in participatory budgeting [PDF]

, 2012
Participation has undergone a communicative shift, which has favoured the organization of new participatory processes based on classic principles of deliberation theory.
Francés, Francisco, Ganuza Fernández, Ernesto   +1 more
core   +2 more sources

Disordered but rhythmic—the role of intrinsic protein disorder in eukaryotic circadian timing

FEBS Letters, EarlyView.
Unstructured domains known as intrinsically disordered regions (IDRs) are present in nearly every part of the eukaryotic core circadian oscillator. IDRs enable many diverse inter‐ and intramolecular interactions that support clock function. IDR conformations are highly tunable by post‐translational modifications and environmental conditions, which ...
Emery T. Usher, Jacqueline F. Pelham
wiley   +1 more source

The political ecology of participatory conservation: institutions and discourse

Journal of Political Ecology, 2015
Increasingly, natural resource conservation programs refer to participation and local community involvement as one of the necessary prerequisites for sustainable resource management.
R. Patrick Bixler, Jampel Dell'Angelo, Orleans Mfune, Hassan Roba   +3 more
doaj   +1 more source

Czech postcommunist trouble with participatory governance. Toward an analysis of the cultural agency of policy discourses

Policy studies, 2019
The article uses the postcommunist context to rethink the argumentative arena of current participatory governance. While citizen empowerment is a crucial component of participatory governance, it has not received much attention in either the policy or ...
Anna P. Durnová
semanticscholar   +1 more source

Function‐driven design of a surrogate interleukin‐2 receptor ligand

FEBS Letters, EarlyView.
Interleukin (IL)‐2 signaling can be achieved and precisely fine‐tuned through the affinity, distance, and orientation of the heterodimeric receptors with their ligands. We designed a biased IL‐2 surrogate ligand that selectively promotes effector T and natural killer cell activation and differentiation. Interleukin (IL) receptors play a pivotal role in
Ziwei Tang, Zelin Cheng, Teng Li, Fulian Wang, Liangminghui Zhang, Xiuxiu He, Lili Liu, Wei Wang, Aibin Liang, Guang Yang   +9 more
wiley   +1 more source