Results 111 to 120 of about 1,348,580 (296)
The urban paradox and the primacy of good governance in Ethiopia: a systematic review
Cogent Social SciencesWhile urbanization is often portrayed as a pathway to economic growth and improved living standards, evidence from Ethiopian cities reveals deep inequalities and governance failures that challenge this view.
Daniel Amente Kenea
doaj +1 more source
The role of miR‐335‐5p in the redifferentiation of BRAF p.V600E thyroid cancers
Molecular Oncology, EarlyView.The BRAF p.V600E mutation promotes thyroid cancer dedifferentiation and radioiodine resistance. Using a network approach, we identified miR‐335‐5p as a key regulator of BRAF‐mutated thyroid tumors. Restoring miR‐335‐5p increased thyroid‐specific gene expression and iodine uptake in cells and organoids.
Valeria Pecce +11 more
wiley +1 more source
Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment
Molecular Oncology, EarlyView.This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley +1 more source
Who rules the waves? : governance and new institutional arrangements in Dutch fisheries management in the context of the European common fisheries policy [PDF]
, 2010 Top down government ruling is perceived as a main contributor to the failure of fisheries management. A change in the governance set up, with a more participatory signature and a change in role and position of the state, the industry and society in ...
van Hoof, L.J.W., Hoof, L.J.W., van
core
Hijacking emergency granulopoiesis: Neutrophil ontogeny and reprogramming in cancer
Molecular Oncology, EarlyView.Neutrophils are highly plastic innate immune cells; their functions in cancer extend beyond the tumour microenvironment. This Review summarises current understanding of neutrophil maturation and heterogeneity and highlights tumour‐induced granulopoiesis as a systemic programme that expands immature, immunosuppressive neutrophils via tumour‐derived ...
Gabriela Marinescu, Yi Feng
wiley +1 more source
Towards Participatory River Governance Through Citizen Science
The concept of a “water governance crisis” manifests distinctly across different regions. In the Global South, particularly in rapidly urbanizing cities, innovative governance models that incorporate community participation are critically ...
Jacob Staines +3 more
core +1 more source
Molecular Oncology, EarlyView.RNA profiling of circulating extracellular vesicles (EVs) from blood samples of men undergoing prostate biopsy identifies transcripts associated with clinically significant prostate cancer. Integrative analysis with public tumor datasets links EV‐derived gene signatures to tumor stage and progression‐free survival, highlighting CASP3, XRCC2, and RIT1 ...
Stefan Werner +14 more
wiley +1 more source
State-society nexus in Brazil and Venezuela and its effect on participatory governance efforts in health and other sectors. [PDF]
Int J Equity Health, 2020 Mahmood Q, Muntaner C.
europepmc +1 more source
Molecular Oncology, EarlyView.The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka +9 more
wiley +1 more source
Frontiers in Political ScienceThe governance of cultural diplomacy remains centralised within state institutions through a soft-power framework that concentrates diplomatic authority in national governments while marginalising countries of the Global South due to structural power ...
Irma Rachmawati Maruf +3 more
doaj +1 more source