Results 131 to 140 of about 952,020 (338)
Molecular Oncology, EarlyView.Both cg12821679MAPRE3 methylation and MAPRE3 expression are significantly associated with overall survival (OS) of non‐small cell lung cancer. Meanwhile, MAPRE3 expression significantly modified the effect of smoking cessation on OS. Smoking cessation benefits OS merely for patients with high MAPRE3 expression.
Chao Chen +14 more
wiley +1 more source
Towards Participatory River Governance Through Citizen Science
The concept of a “water governance crisis” manifests distinctly across different regions. In the Global South, particularly in rapidly urbanizing cities, innovative governance models that incorporate community participation are critically ...
Jacob Staines +3 more
core +1 more source
The urban paradox and the primacy of good governance in Ethiopia: a systematic review
Cogent Social SciencesWhile urbanization is often portrayed as a pathway to economic growth and improved living standards, evidence from Ethiopian cities reveals deep inequalities and governance failures that challenge this view.
Daniel Amente Kenea
doaj +1 more source
International Journal of the Commons, 2018 In this paper, we argue that, like a three-legged stool, participatory programs require three elements for stability: a supply of participatory institutions, a demand from citizens to participate, and citizens with capabilities for participation.
Forrest Fleischman +1 more
doaj +1 more source
Molecular Oncology, EarlyView.Many patients with urothelial cancer do not benefit from treatment with pembrolizumab, while at risk of severe side effects. Changes in the levels of circulating tumor DNA early during treatment, measured by a simple and affordable assay that can be easily implemented in the clinic, can be used as a prognostic tool to identify these patients.
Youssra Salhi +14 more
wiley +1 more source
Explainable AI in education: A multi-stakeholder approach to transparency and ethical practice
IUL ResearchIntegrating AI into education makes explainability an ethical imperative. This analysis examines competency requirements for 5 stakeholder groups – learners, educators, parents, system leaders, and developers – while evaluating capacity-building ...
Jessica Niewint-Gori
doaj +1 more source
Molecular Oncology, EarlyView.The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka +9 more
wiley +1 more source
Tumor B‐cell infiltration in platinum‐treated advanced muscle‐invasive urothelial carcinoma
Molecular Oncology, EarlyView.Bladder tumors with higher pretreatment memory B‐cell infiltration were linked to longer survival after cisplatin chemotherapy, but not carboplatin. These tumors also showed more organized immune structures (tertiary lymphoid structures) and a shared pro‐inflammatory B‐cell‐rich community, suggesting that memory B cells may help identify patients most ...
Konrad Stawiski +10 more
wiley +1 more source
FEBS Open Bio, EarlyView.In this study, we developed a deep learning method for mitotic figure counting in H&E‐stained whole‐slide images and evaluated its prognostic impact in 13 external validation cohorts from seven different cancer types. Patients with more mitotic figures per mm2 had significantly worse patient outcome in all the studied cancer types except colorectal ...
Joakim Kalsnes +32 more
wiley +1 more source
Ecosystems and PeopleDespite the growing emphasis on ontological pluralism in environmental policy debates, innovation within national state environmental governance and management remains limited.
Thomas Rickard +2 more
doaj +1 more source