Results 141 to 150 of about 952,020 (338)

Chameleon sequences reveal structural effects in proteins representing micelle‐like distribution of hydrophobicity

open access: yesFEBS Open Bio, EarlyView.
Amino acids sequence of two different proteins with the same sequence (chameleon sequence—black boxes) represent in 3D structure of the proteins different secondary structures: HHHH—helical and BBB—Beta‐structural. The chains folded in water environment adopt different III‐order structures in which the chameleon fragments appear to adopt similar status
Irena Roterman   +4 more
wiley   +1 more source

Smarter Cities, Stronger Heritage: Toward Participatory and Knowledge-Driven Governance for Cultural Preservation in Morocco

open access: yesEngineering Proceedings
This paper explores how Smart Urban Governance, Smart Knowledge Management (Smart KM), and participatory digital tools can reshape cultural heritage rehabilitation in Morocco. Using a qualitative, multi-method approach including comparative case studies,
Douae El Hadraoui, Naila Amrous
doaj   +1 more source

Exon 7 splicing of ERα predicts poor prognosis and increases phenotypic heterogeneity in luminal a subtype breast cancer

open access: yesFEBS Open Bio, EarlyView.
ERα splice variant ERα∆7 lacks the C‐terminus, and its expression may change phenotypes of breast cancers. Our results showed that ERα∆7 is found in the luminal A subtype, and elevated ERα∆7 levels are linked to improved cell survival with lower proliferation and migration.
Long Wai Tsui   +10 more
wiley   +1 more source

Iron homeostasis disruption and lipid peroxidation in skeletal muscle during short‐term immobilization

open access: yesFEBS Open Bio, EarlyView.
14‐day casting‐induced immobilization reduced gastrocnemius muscle mass and increased non‐heme iron and ferritin heavy chain levels. Despite iron accumulation, transferrin receptor 1 and iron regulatory protein 2 were paradoxically upregulated. Lipid peroxidation was elevated without compensatory antioxidant responses.
Haruka Yokogawa   +2 more
wiley   +1 more source

Evaluating governance and participatory processes in Natura 2000: lessons learned and guidance for future prospects [PDF]

open access: yes, 2012
In recent years, participatory approaches have been incorporated in decision-making processes as a way to strengthen the bonds between diverse areas of knowledge and social actors in natural resources management and environmental governance.
Etxano Gandariasbeitia, Iker   +2 more
core  

The skills required for transition to university and study in biological sciences: A student perspective

open access: yesFEBS Open Bio, EarlyView.
Bioscience students were asked for their opinions on the value and teaching of skills. 204 responded that teamwork, time management and study skills are necessary to reach University, that scientific writing, research, laboratory and presentation skills are taught effectively during their studies, while other skills are gained inherently through study ...
Janella Borrell, Susan Crennell
wiley   +1 more source

Community-based governance in social-ecological systems: An inquiry into the marginalisation of Landcare in Victoria, Australia

open access: yes, 2012
Environmental governance regimes affect the adaptive capacity of social-ecological systems. By enabling actors with differing knowledge, values and interests to understand complex problems, agree on solutions and integrate their actions, network forms of
Colliver, Ross
core  

Empowerment or legitimation? The Angolan Conselhos de Auscultação e Concertação Social

open access: yesRevista Iberoamericana de Estudios de Desarrollo, 2012
The Conselhos de Auscultação e Concertação Social (CACS) of Angola are spaces of participatory governance, where local authorities have to consult and be accountable to society.
Hueso González, Andrés
doaj  

Mass spectrometry based identification of AMP‐O‐Tris generated by Thermococcus onnurineus Cas10

open access: yesFEBS Open Bio, EarlyView.
Isolated Thermococcus onnurineus Cas10 generates the noncanonical ATP‐derived product AMP‐O‐Tris while in Tris‐containing buffer as identified via mass spectrometry, revealing relaxed nucleophile selectivity under isolated conditions. These findings suggest that multiprotein Csm complex assembly restricts Cas10 reactivity toward canonical cyclic ...
Su‐Jin Lee   +6 more
wiley   +1 more source

Why human connection is the true metric of research success

open access: yesFEBS Open Bio, EarlyView.
Human‐centred mentorship can be shaped by mentor attributes, actions, intrinsic drive and career ambition. Drawing on reflections across Singapore and France, as well as workshop insights from FEBS‐IUBMB ENABLE 2024, this article shows that human‐centred mentorship creates the conditions for sustainable growth, well‐being and retention in research ...
Timothy Lin Yun Tan   +3 more
wiley   +1 more source

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