Results 101 to 110 of about 1,348,580 (296)

Leucine‐rich glioma inactivated 1 (LGI1) is a ganglioside‐binding protein

FEBS Letters, EarlyView.
Neuronal hyperexcitability associated with a decrease/absence of the extracellular protein LGI1 has been suggested to be primarily due to the downregulation of Kv1 channel expression. The molecular mechanisms underlying this decrease have not yet been elucidated.
Kévin Debreux, Christian Lévêque, Fodil Azzaz, Marion Sangiardi, Sarosh R Irani, Michael Seagar, Jacques Fantini, Oussama El Far   +7 more
wiley   +1 more source

Community-based governance in social-ecological systems: An inquiry into the marginalisation of Landcare in Victoria, Australia [PDF]

, 2012
Environmental governance regimes affect the adaptive capacity of social-ecological systems. By enabling actors with differing knowledge, values and interests to understand complex problems, agree on solutions and integrate their actions, network forms of
Colliver, Ross
core  

The Role of Participatory Planning and Design in Addressing the UN Sustainable Development Goals

Urban Planning
This editorial explores the role of participatory planning and design in addressing the United Nations Sustainable Development Goals (UN SDGs) within urban, regional, and rural contexts, which is the focus of this thematic issue.
Hilary Davis, Joel Fredericks, Marcus Foth, Glenda Amayo Caldwell, Callum Parker   +4 more
doaj   +1 more source

Metastatic niche shaped by host factors influences disseminated cancer cell fate

FEBS Letters, EarlyView.
Metastasis is shaped not only by cancer cells but also by the environments they encounter. This review explores how factors such as aging, diet, the microbiome, lifestyle, and environmental exposures remodel organ‐specific niches in the lung, liver, bone, and brain, influencing where metastatic cells survive, remain dormant, or grow, and ultimately ...
Gwennan Delyth Ward, Álvaro Ruiz‐Tabas, Patricia Altea‐Manzano   +2 more
wiley   +1 more source

Reframing brownfield redevelopment through a community participation framework: a comparative review of governance models

Journal of Asian Architecture and Building Engineering
This study offers a comparative conceptual review of brownfield redevelopment (BFR) through the lens of community participation frameworks. Moving beyond traditional scoping reviews, we analyze how participatory models – particularly Arnstein’s Ladder of
Eunki Kang, Yoon-Jeoung Shin, Eun Joo Park   +2 more
doaj   +1 more source

Invisible but not inaccessible—Revealing transient oligomers formed by intrinsically disordered proteins with solution NMR and complementary methods

FEBS Letters, EarlyView.
Transient oligomers formed by intrinsically disordered proteins may be ‘invisible’ to direct detection yet remain accessible to solution NMR through equilibrium‐exchange measurements and pressure‐jump experiments. Complementary methods report on mass, stoichiometry, selected distance distributions, morphology, and internal packing.
Martin D. Gelenter, Ad Bax
wiley   +1 more source

Membrane composition and thermodynamic identity as boundaries of life for synthetic cell research

FEBS Letters, EarlyView.
What makes a cell a cell? The boundary of a living cell is not just a wall. Read as a Markov blanket, the membrane separates internal from external states, generating identity and non‐equilibrium order. Can this identity be rebuilt from scratch in a synthetic cell?
Caterina Presutti, Bert Poolman
wiley   +1 more source

Explainable AI in education: A multi-stakeholder approach to transparency and ethical practice

IUL Research
Integrating AI into education makes explainability an ethical imperative. This analysis examines competency requirements for 5 stakeholder groups – learners, educators, parents, system leaders, and developers – while evaluating capacity-building ...
Jessica Niewint-Gori
doaj   +1 more source

Inhibition of dipeptidyl peptidase 7 impairs lysophagy in LLOMe‐treated HepG2 cells

FEBS Letters, EarlyView.
DPP7 inhibition delays ubiquitin‐dependent lysophagy by attenuating ubiquitin accumulation and the recruitment of SQSTM1 and LC3 to damaged lysosomes, resulting in delayed clearance of damaged lysosomes and impaired restoration of lysosomal homeostasis. Created using FigureLabs (Certificate ID: FL‐PUB‐20260922‐Z99XNX).
Na Yeon Park, Inho Kwon, Yong Hwan Kim, Ji‐Eun Bae, Joon Bum Kim, Seong Hyun Kim, Sungho Maeng, Doo Sin Jo, Dong‐Hyung Cho   +8 more
wiley   +1 more source

Complexity, Governance and Networks: Introduction to the Inaugural Issue

, 2014
From the introduction: 1. Yet Another Journal? Why is it necessary to publish a new journal about complexity, governance, and networks? There has been an increasing interest in complexity, governance, and network studies in recent decades.
Morçöl, Göktuğ, Gerrits, Lasse, Teisman, Geert   +2 more
core   +1 more source