Results 111 to 120 of about 124,534 (311)

Interrogating the immune landscape of microsatellite stable RAS‐mutated colon cancer

open access: yesMolecular Oncology, EarlyView.
COLOSSUS project RAS‐mutated MSS colon cancer study explored transcriptomics and immune cell density by immunohistochemistry (IHC), Immunoscore (IS), ISIC/TuLIS scores, mutation counts, and detected different prevalences but similar microenvironment composition across immune markers with clinical relevance for future immunotherapy combination ...
Rodrigo Dienstmann   +61 more
wiley   +1 more source

PARTICIPATORY RESEARCH METHODS FOR TECHNOLOGY EVALUATION: A MANUAL FOR SCIENTISTS WORKING WITH FARMERS

open access: yes
This manual presents methods that enable agricultural scientist and farmers to evaluate technologies/practices jointly. The methods are specifically designed for participatory research on germplasm and soil fertility technologies, and they are ...
Bellon, Mauricio R.
core  

'Thinking-through-Complicity' with Te Iwi o Ngāti Hauiti: Towards a Critical Use of Participatory Video for Research

open access: yes, 2012
This thesis explores some of the seductions and dangers of participatory video for research (PVR) involving Indigenous Māori and Pākehā research partners.
Kindon, Sara Louise
core  

Discussing the use of participatory methods with young people on the move

open access: yesFrontiers in Human Dynamics
IntroductionAt the end of 2023, 117.3 million people were forcibly displaced worldwide. Despite the scale of this phenomenon, young migrants aged 15-25 remain largely invisible in both research and policy, as illustrated by the absence of age ...
Glenda Santana de Andrade   +2 more
doaj   +1 more source

Somatic mutational landscape in von Hippel–Lindau familial hemangioblastoma

open access: yesMolecular Oncology, EarlyView.
The causes of central nervous system (CNS) hemangioblastoma in Von Hippel–Lindau (vHL) disease are unclear. We used Whole Exome Sequencing (WES) on familial hemangioblastoma to investigate events that underlie tumor development. Our findings suggest that VHL loss creates a permissive environment for tumor formation, while additional alterations ...
Maja Dembic   +5 more
wiley   +1 more source

Exploring the impacts of woodland management on ecosystem services – a deliberative method

open access: yesEcosystems and People
There is a need for operational decision-making methodologies applicable at local management scales which are inclusive and enable the integration of plural values, knowledges and perspectives of co-produced ecosystem services.
Antonia Eastwood   +11 more
doaj   +1 more source

Establishment of a humanized patient‐derived xenograft mouse model of high‐grade serous ovarian cancer for preclinical evaluation of combination immunotherapy

open access: yesMolecular Oncology, EarlyView.
We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric   +10 more
wiley   +1 more source

Transcriptional profiling of circulating extracellular vesicles from prebiopsy prostate cancer patients

open access: yesMolecular Oncology, EarlyView.
RNA profiling of circulating extracellular vesicles (EVs) from blood samples of men undergoing prostate biopsy identifies transcripts associated with clinically significant prostate cancer. Integrative analysis with public tumor datasets links EV‐derived gene signatures to tumor stage and progression‐free survival, highlighting CASP3, XRCC2, and RIT1 ...
Stefan Werner   +14 more
wiley   +1 more source

Weaving the threads of time: narrative methods in participatory research

open access: yes, 2012
Once upon a time...Commencing from the stance that all stories may be retold anew, and that a given event embraces the multiple rather than singular as discussed in the work of Jean Clandinin and Michael Connelly (2000, p.
Jones, Janice Kathleen
core  

Participatory planning and extension: an agroforestry case study from plateau state, Nigeria [PDF]

open access: yes, 1999
In 1991 and 1992 the author and the Jos Plateau Environmental Resources Development Programme (JPERDP), embarked on a rural development project in northern Nigeria.
Hunter, Barry Wayne
core  

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