Results 91 to 100 of about 74,562 (313)
Revue de Géographie AlpineParticipatory science is an alternative to certain mountain practices. At local, it rests on collaborations between scientists and citizens. In France, the Mercantour National Park, a unique territory, is an interesting case for study.
Alain Schoeny
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Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system
FEBS Letters, EarlyView.Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley +1 more source
FEBS Letters, EarlyView.Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura +2 more
wiley +1 more source
Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation
FEBS Letters, EarlyView.Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz +11 more
wiley +1 more source
, 2011 Changes in the environment require a range of responses and adaptations at different levels. One of the levels where adaptation is needed is at the community level in developing countries.
Castro, Luis Miguel
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Building Resilience to Chronic Landslide Hazard Through Citizen Science
Frontiers in Earth Science, 2019 Landslides disrupt livelihoods, cause loss of human lives and damages to property and infrastructure. In the case of Nepal, the destructive impact of landslides has been steadily increasing as a result of the rising occupation of marginal land and ...
Katarzyna Cieslik +7 more
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pH‐mediated activation of the lysosomal arginine sensor SLC38A9
FEBS Letters, EarlyView.Cells monitor nutrient levels via the lysosomal transporter SLC38A9 to activate the mechanistic target of rapamycin complex 1 (mTORC1). This study reveals that SLC38A9 function is regulated by pH. We identified histidine 544 as a critical pH sensor that undergoes conformational changes to control amino acid efflux from lysosomes; therefore, it ...
Xuelang Mu, Ampon Sae Her, Tamir Gonen
wiley +1 more source
The human gut microbiome across the life course
FEBS Letters, EarlyView.Despite significant individual variation and continuous change throughout life, the human gut microbiome follows some life stage‐specific trends. This article provides a brief overview of how gut microbiome composition shifts across different phases of life. Created in BioRender. Özkurt, E. (2026) https://BioRender.com/8q4nrnc.
Alise J. Ponsero +4 more
wiley +1 more source
Participatory Science Newsletter 2025_01_30 [PDF]
Welcome to this inaugural Participatory Science newsletter, a new publication from the University of New Hampshire (UNH) Cooperative Extension that will focus on participatory science activities happening at UNH and among community partners and ...
Eberhardt, Alyson L., Clyde, Malin
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Cidades, Comunidades e TerritórioParticipatory science, also known as citizen science, is an open science practice in which individuals, both affiliated and unaffiliated with scientific institutions, collaborate on a scientific project.
Diego Torres +3 more
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